Medline ® Abstract for Reference 8
of 'Diagnosis of psychiatric disorders in patients with cancer'
Emotional distress in cancer patients: the Edinburgh Cancer Centre symptom study.
Strong V, Waters R, Hibberd C, Rush R, Cargill A, Storey D, Walker J, Wall L, Fallon M, Sharpe M
Br J Cancer. 2007;96(6):868. Epub 2007 Feb 20.
To: (1) estimate the prevalence of clinically significant emotional distress in patients attending a cancer outpatient department and (2) determine the associations between distress and demographic and clinical variables, we conducted a survey of outpatients attending selected clinics of a regional cancer centre in Edinburgh, UK. Patients completed the Hospital Anxiety and Depression Scale (HADS) on touch-screen computers and the scores were linked to clinical variables on the hospital database. Nearly one quarter of the cancer outpatients 674 out of 3071 (22%; 95% confidence interval (CI) 20-23%) met our criterion for clinically significant emotional distress (total HADS score 15 or more). Univariate analysis identified the following statistically significant associations: age<65, female gender, cancer type and extent of disease. Multivariate analysis indicated that age<65 (odds ratio 1.41; 95% CI 1.18-1.69), female gender (odds ratio 1.58; 95% CI 1.31-1.92) and active disease (odds ratio 1.72; 95% CI 1.43-2.05) but not cancer diagnosis, were the independent predictors of clinically significant emotional distress. Services to treat distress in cancer patients should be organised to target patients by characteristics other than theircancer diagnosis.
School of Molecular and Clinical Medicine, Cancer Research UK and The University of Edinburgh Cancer Research Centre, The Western General Hospital, Crewe Road, Edinburgh EH4 2XR, UK. firstname.lastname@example.org