Medline ® Abstract for Reference 46
of 'Convulsive status epilepticus in adults: Treatment and prognosis'
Sodium valproate vs phenytoin in status epilepticus: a pilot study.
Misra UK, Kalita J, Patel R
Sixty-eight patients with convulsive status epilepticus (SE) were randomly assigned to two groups to study the efficacy of sodium valproate (VPA) and phenytoin (PHT). Seizures were aborted in 66% in the VPA group and 42% in the PHT group. As a second choice in refractory patients, VPA was effective in 79% and PHT was effective in 25%. The side effects in the two groups did not differ. Sodium valproate may be preferred in convulsive SE because of its higher efficacy.
Department of Neurology, Sanjay Gandhi PGIMS, Lucknow, India. firstname.lastname@example.org