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Medline ® Abstract for Reference 155

of 'Convulsive status epilepticus in adults: Treatment and prognosis'

155
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Acute symptomatic seizures and hippocampus damage: DWI and MRS findings.
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Parmar H, Lim SH, Tan NC, Lim CC
SO
Neurology. 2006;66(11):1732.
 
The authors describe diffusion-weighted imaging (DWI) and magnetic resonance spectroscopy (MRS) changes in the hippocampus within 48 hours of acute symptomatic seizures or status epilepticus in 12 patients. DWI showed increased signal and a decreased apparent diffusion coefficient (ADC) in all patients, with corresponding lactate detected on MRS in six patients and EEG seizure activity in nine patients. On follow-up, the atrophic hippocampus had an increased ADC in six patients. DWI and MRS may predict development of hippocampal sclerosis.
AD
Department of Neuroradiology, National Neuroscience Institute, Singapore.
PMID