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Medline ® Abstract for Reference 143

of 'Convulsive status epilepticus in adults: Treatment and prognosis'

Systemic complications of status epilepticus--An update.
Hocker S
Epilepsy Behav. 2015 Aug;49:83-7. Epub 2015 May 9.
Systemic complications occur at every stage of status epilepticus, involve every organ system, and may worsen outcome. Initially, there is a massive catecholamine release and hyperadrenergic state that may result in neurocardiogenic, pulmonary, and, sometimes, musculoskeletal or renal injury. Further medical complications accompany the various treatments used to abort the seizures including the use of nonanesthetic antiseizure drugs and high-dose anesthetic infusions. Later, sequelae of prolonged immobility and critical illness occur and add to the cumulative morbidity of these patients. Clinicians should follow a protocol to guide screening for early markers of systemic injury, complications of specific pharmacologic and adjunctive treatments, and periodic surveillance for complications related to prolonged immobility. This article is part of a Special Issue entitled "Status Epilepticus".
Division of Critical Care Neurology, Mayo Clinic, Rochester, MN, USA. Electronic address: Hocker.Sara@Mayo.Edu.