Medline ® Abstract for Reference 119
of 'Convulsive status epilepticus in adults: Treatment and prognosis'
Use of dietary therapy for status epilepticus.
Kossoff EH, Nabbout R
J Child Neurol. 2013;28(8):1049.
One of the newest and yet fastest growing indications for dietary therapy is the emergency treatment of refractory status epilepticus. Ten retrospective publications since 2008 have reported benefits in 32 children and adults, of whom 25 (78%) became seizure-free. Most of the patients who responded did so within 7 to 10 days of the initiation of nasogastrically administered ketogenic formulas. Encephalitis and febrile-illness related epilepsy syndrome causing status epilepticus highly refractory to antiepileptic drugs may be particularly amenable to dietary treatment. Prospective, multicenter studies are under way to help clarify who best will respond, how quickly, and the optimal diet duration after success.
1John M. Freeman Pediatric Epilepsy Center, Departments of Neurology and Pediatrics, Johns Hopkins Medical Institutions, Baltimore, MD, USA.