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Medline ® Abstract for Reference 115

of 'Convulsive status epilepticus in adults: Treatment and prognosis'

115
TI
Resective surgery to treat refractory status epilepticus in children with focal epileptogenesis.
AU
Alexopoulos A, Lachhwani DK, Gupta A, Kotagal P, Harrison AM, Bingaman W, Wyllie E
SO
Neurology. 2005 Feb;64(3):567-70.
 
Prolonged high-dose suppressive therapy (HDST) is a mainstay in the management of refractory status epilepticus (RSE), albeit with high morbidity and mortality. The authors studied 10 patients who were carefully selected for epilepsy surgery after failing prolonged (>2 weeks) HDST. Status epilepticus was stopped acutely in all of them with no mortality and no substantial morbidity. At follow-up (median 7 months), 7 (70%) of 10 patients were seizure free, and 3 (30%) of 10 had significant improvement in their epilepsy.
AD
Department of Neurology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
PMID