Hypoglycemia associated with clonidine testing for growth hormone deficiency

C Huang; K Banerjee; E Sochett; K Perlman; D Wherrett; D Daneman

doi:10.1067/mpd.2001.116276

Hypoglycemia associated with clonidine testing for growth hormone deficiency

J Pediatr. 2001 Aug;139(2):323-4. doi: 10.1067/mpd.2001.116276.

Authors

C Huang¹, K Banerjee, E Sochett, K Perlman, D Wherrett, D Daneman

Affiliation

¹ Division of Endocrinology, Department of Pediatrics, University of Toronto and the Hospital for Sick Children, Toronto, Ontario, Canada.

PMID: 11487765
DOI: 10.1067/mpd.2001.116276

Abstract

We have observed 4 cases of hypoglycemia associated with clonidine stimulation of growth hormone secretion; only one patient had growth hormone deficiency. Significant drowsiness after administration of clonidine may prolong the period of fasting in these children and mask early signs and symptoms, leading to severe hypoglycemia.

Publication types

Case Reports

MeSH terms

Administration, Oral
Adolescent
Blood Glucose / drug effects*
Child, Preschool
Clonidine / administration & dosage
Clonidine / adverse effects*
Fasting / metabolism*
Female
Growth Hormone / deficiency*
Humans
Hypoglycemia / chemically induced*
Male
Sleep Stages / drug effects

Substances

Blood Glucose
Growth Hormone
Clonidine