Clinical manifestations, pathologic features, and diagnosis of hepatosplenic T cell lymphoma
- Arnold S Freedman, MD
Arnold S Freedman, MD
- Section Editor — Lymphoproliferative Disorders
- Professor of Medicine
- Harvard Medical School
- Jon C Aster, MD
Jon C Aster, MD
- Professor of Pathology
- Harvard Medical School
The peripheral T cell lymphomas (PTCLs) are a heterogeneous group of generally aggressive neoplasms that constitute less than 15 percent of all non-Hodgkin lymphomas (NHLs) in adults. (See "Classification of the hematopoietic neoplasms".)
Among these, in decreasing frequency of occurrence, are:
●Peripheral T cell lymphoma, not otherwise specified (NOS)
●Anaplastic large cell lymphoma, primary systemic type
●Angioimmunoblastic T cell lymphomaTo continue reading this article, you must log in with your personal, hospital, or group practice subscription. For more information on subscription options, click below on the option that best describes you:
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- CLINICAL FEATURES
- Patterns of involvement
- - Spleen
- - Liver
- - Bone marrow
- Genetic features
- DIFFERENTIAL DIAGNOSIS
- Splenic marginal zone lymphoma
- T cell large granular lymphocyte leukemia
- Aggressive NK leukemia/lymphoma
- Acute lymphoblastic leukemia
- Other gamma/delta lymphomas