Clinical diagnosis of stroke subtypes
- Louis R Caplan, MD
Louis R Caplan, MD
- Professor of Neurology
- Harvard Medical School
The two broad categories of stroke, hemorrhage and ischemia, are diametrically opposite conditions: hemorrhage is characterized by too much blood within the closed cranial cavity, while ischemia is characterized by too little blood to supply an adequate amount of oxygen and nutrients to a part of the brain . Each of these categories can be divided into subtypes that have somewhat different causes, clinical pictures, clinical courses, outcomes, and treatment strategies. As an example, intracranial hemorrhage can be caused by intracerebral hemorrhage (ICH), also called parenchymal hemorrhage, which involves bleeding directly into brain tissue, and subarachnoid hemorrhage (SAH), which involves bleeding into the cerebrospinal fluid that surrounds the brain and spinal cord .
This topic will review the categories of stroke and their clinical diagnosis. An overview of the evaluation of stroke and the clinical manifestations of transient cerebral ischemia are discussed separately. (See "Overview of the evaluation of stroke" and "Definition, etiology, and clinical manifestations of transient ischemic attack".)
Stroke is classified into the following subtypes: intracerebral hemorrhage, subarachnoid hemorrhage, and brain ischemia due to thrombosis, embolism, or systemic hypoperfusion.
The classification of stroke is discussed in detail separately. (See "Etiology, classification, and epidemiology of stroke".) The subtypes are reviewed here briefly.
Intracerebral hemorrhage — Bleeding in intracerebral hemorrhage (ICH) is usually derived from arterioles or small arteries. The bleeding is directly into the brain, forming a localized hematoma that spreads along white matter pathways. Accumulation of blood occurs over minutes or hours and the neurologic symptoms usually increase gradually over minutes or a few hours. In contrast to brain embolism and SAH, the neurologic symptoms do not begin abruptly and are not maximal at onset (figure 1).To continue reading this article, you must log in with your personal, hospital, or group practice subscription. For more information on subscription options, click below on the option that best describes you:
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- Intracerebral hemorrhage
- Subarachnoid hemorrhage
- Brain ischemia
- DISTINGUISHING STROKE SUBTYPES
- Clinical course
- Ecology and risk factors
- - Age, gender, and race
- - Heart disease
- - Hypertension
- - Smoking
- - Other risk factors
- Other historical features
- - Previous transient ischemic attack
- - Activity at the onset or just before the stroke
- - Associated symptoms
- Silent brain infarcts
- General physical examination
- Neurologic examination
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