Classification and prognosis of pulmonary hypertension in adults
- Lewis J Rubin, MD
Lewis J Rubin, MD
- Adjunct Professor of Medicine
- College of Physicians and Surgeons, Columbia University
- William Hopkins, MD
William Hopkins, MD
- Associate Professor of Medicine
- University of Vermont College of Medicine
Pulmonary hypertension (PH) is defined as an elevated mean arterial pressure ≥25 mmHg at rest [1,2]. PH has several etiologies and can be a progressive, fatal disease, if untreated.
The classification and prognosis of PH are reviewed here. The epidemiology, pathogenesis, clinical features, diagnostic evaluation, and treatment of PH are discussed separately. (See "The epidemiology and pathogenesis of pulmonary arterial hypertension (Group 1)" and "Clinical features and diagnosis of pulmonary hypertension in adults" and "Treatment of pulmonary hypertension in adults".)
●Group 1 – Pulmonary arterial hypertension (PAH)
●Group 2 – PH due to left heart disease
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- Group 1 pulmonary arterial hypertension (PAH)
- Group 2 PH (left heart disease)
- Group 3 PH (lung disease)
- Group 4 PH (thromboembolic disease)
- Group 5 PH (multifactorial)
- NATURAL HISTORY AND PROGNOSIS
- Group 1 PAH
- - Prognosis without therapy
- - Effect of treatment
- - Prognostic factors
- - Cause of death
- Groups 2 to 5
- INFORMATION FOR PATIENTS
- SUMMARY AND RECOMMENDATIONS