Chagas disease in the immunosuppressed host
- Caryn Bern, MD, MPH
Caryn Bern, MD, MPH
- Professor, Global Health Sciences
- University of California, San Francisco
Chagas disease is caused by infection with the protozoan parasite Trypanosoma cruzi; the major manifestations are Chagas cardiomyopathy and gastrointestinal disease .
Issues related to Chagas in the setting of immunosuppression are reviewed here. Issues relating to acute and chronic Chagas infection are discussed separately. (See "Chagas disease: Acute and congenital Trypanosoma cruzi infection" and "Chagas disease: Chronic Trypanosoma cruzi infection".)
Issues related to epidemiology and prevention of Chagas disease are discussed separately. (See "Chagas disease: Epidemiology and prevention".)
Issues related to cardiac and gastrointestinal Chagas are discussed separately. (See "Chagas heart disease: Clinical manifestations and diagnosis" and "Chagas heart disease: Treatment and prognosis" and "Chagas gastrointestinal disease".)
FORMS OF DISEASE
Forms of Chagas disease in immunosuppressed hosts include reactivation of T. cruzi infection (in HIV-infected patients and patients on immunosuppressive medications) and donor-derived infection in organ transplant recipients.To continue reading this article, you must log in with your personal, hospital, or group practice subscription. For more information on subscription options, click below on the option that best describes you:
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- FORMS OF DISEASE
- Reactivation of chronic Chagas in immunosuppressed patients
- - Clinical manifestations
- HIV-infected patients
- Transplant recipients
- - Diagnosis
- - Monitoring
- Donor-derived acute Chagas in organ transplant recipients
- - Clinical manifestations
- - Diagnosis
- - Monitoring
- TREATMENT AND PREVENTION
- SOCIETY GUIDELINE LINKS
- SUMMARY AND RECOMMENDATIONS