Chagas disease in the immunosuppressed host
- Caryn Bern, MD, MPH
Caryn Bern, MD, MPH
- Professor, Global Health Sciences
- University of California, San Francisco
Chagas disease is caused by infection with the protozoan parasite Trypanosoma cruzi; the major manifestations are Chagas cardiomyopathy and gastrointestinal disease .
Issues related to Chagas in the setting of immunosuppression are reviewed here. Issues relating to acute and chronic Chagas infection are discussed separately. (See "Chagas disease: Acute and congenital Trypanosoma cruzi infection" and "Chagas disease: Chronic Trypanosoma cruzi infection".)
Issues related to epidemiology and prevention of Chagas disease are discussed separately. (See "Chagas disease: Epidemiology and prevention".)
Issues related to cardiac and gastrointestinal Chagas are discussed separately. (See "Chagas heart disease: Clinical manifestations and diagnosis" and "Chagas heart disease: Treatment and prognosis" and "Chagas gastrointestinal disease".)
FORMS OF DISEASE
Forms of Chagas disease in immunosuppressed hosts include reactivation of T. cruzi infection (in HIV-infected patients and patients on immunosuppressive medications) and donor-derived infection in organ transplant recipients.
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- FORMS OF DISEASE
- Reactivation of chronic Chagas in immunosuppressed patients
- - Clinical manifestations
- HIV-infected patients
- Transplant recipients
- - Diagnosis
- - Monitoring
- Donor-derived acute Chagas in organ transplant recipients
- - Clinical manifestations
- - Diagnosis
- - Monitoring
- TREATMENT AND PREVENTION
- SOCIETY GUIDELINE LINKS
- SUMMARY AND RECOMMENDATIONS