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Cervical intraepithelial neoplasia: Ablative therapies

Nicholas P Taylor, MD
Section Editor
Barbara Goff, MD
Deputy Editor
Sandy J Falk, MD, FACOG


Cervical intraepithelial neoplasia (CIN) is a premalignant cervical disease that is also called cervical dysplasia or cervical squamous intraepithelial lesions (CSIL). (See "Cervical intraepithelial neoplasia: Terminology, incidence, pathogenesis, and prevention", section on 'Terminology'.)

Treatment of CIN can either be excisional (ie, conization) or ablative. Ablative modalities are solely for treatment, while excisional therapy provides diagnostic information as well as therapeutic benefit.

Ablative therapies of the cervix will be discussed in this topic review. In addition, choosing between excision and ablation, as well as between ablative methods, will be reviewed. Excisional methods for CIN treatment are discussed elsewhere. (See "Cervical intraepithelial neoplasia: Procedures for cervical conization".)


American Society for Colposcopy and Cervical Pathology guidelines include ablative therapy as an option for women with [1,2]:

Persistent CIN 1 for two or more years (excision is preferred if colposcopy is inadequate, endocervical curettage is ungraded or positive for CIN 2,3 [1], or if previously treated for CIN)

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Literature review current through: Nov 2017. | This topic last updated: Dec 04, 2017.
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