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Causes of pulmonary eosinophilia

Amy D Klion, MD
Peter F Weller, MD, MACP
Section Editor
Bruce S Bochner, MD
Deputy Editor
Helen Hollingsworth, MD


Eosinophilic lung diseases are a heterogeneous group of disorders that share the feature of abnormally increased numbers of eosinophils within the pulmonary airways and parenchyma [1-3]. The defining characteristics needed for the diagnosis of pulmonary eosinophilia include [4-6]:

Peripheral blood eosinophilia with abnormalities on pulmonary imaging studies

Lung tissue eosinophilia demonstrated in transbronchial or open lung biopsies

Increased eosinophils in bronchoalveolar lavage (BAL) fluid (eg, >10 percent)

Peripheral blood eosinophils are, by no means, uniformly increased in all types of eosinophilic lung diseases [7,8], and conventional chest radiographs may fail to detect lung parenchymal disease [9].

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Literature review current through: Nov 2017. | This topic last updated: Nov 02, 2017.
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