Abstract
Objectives:
The aim of the study was to report 4 patients with Parkinson disease (PD) and On-period blepharospasm (BS).
Methods:
We analyzed patients with PD and motor fluctuations who developed BS in several different centers in Latin America.
Results:
Four patients had BS while in the ON periods.
Conclusions:
Blepharospasm in the On period in patients with PD is extremely uncommon, and our series is the only one to describe such association.
MeSH terms
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Aged
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Antiparkinson Agents / administration & dosage
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Antiparkinson Agents / adverse effects
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Blepharospasm / chemically induced
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Blepharospasm / drug therapy*
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Blepharospasm / etiology*
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Botulinum Toxins, Type A / adverse effects
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Botulinum Toxins, Type A / therapeutic use
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Carbidopa / adverse effects
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Carbidopa / therapeutic use
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Drug Combinations
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Dyskinesias / drug therapy
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Dyskinesias / physiopathology
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Humans
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Levodopa / administration & dosage*
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Levodopa / adverse effects*
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Levodopa / therapeutic use
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Male
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Middle Aged
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Parkinson Disease / drug therapy*
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Parkinson Disease / physiopathology*
Substances
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Antiparkinson Agents
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Drug Combinations
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carbidopa, levodopa drug combination
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Levodopa
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Botulinum Toxins, Type A
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onabotulinum toxin A
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Carbidopa