Baclofen poisoning in children

Vet Hum Toxicol. 1994 Oct;36(5):448-50.

Abstract

Six cases of acute baclofen (LIORESAL) overdose in children are reported. Rapid onset of central nervous system depression with respiratory depression was present to a greater or lesser degree in all patients. Agitation, convulsions and ataxia were also seen. The entire cohort responded to supportive management. An accurate assessment of the quantity of drug ingested was not possible. The need for education on safe drug storage and disposal is emphasized.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Ataxia / chemically induced
  • Baclofen / poisoning*
  • Central Nervous System / drug effects*
  • Child
  • Child, Preschool
  • Cohort Studies
  • Drug Overdose
  • Female
  • Humans
  • Longitudinal Studies
  • Male
  • Respiratory System / drug effects
  • Seizures / chemically induced
  • South Africa

Substances

  • Baclofen