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Medline ® Abstract for Reference 88

of 'Approach to acute abdominal pain in pregnant and postpartum women'

88
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Incidence of stroke and myocardial infarction in women of reproductive age.
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Petitti DB, Sidney S, Quesenberry CP Jr, Bernstein A
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Stroke. 1997;28(2):280.
 
BACKGROUND AND PURPOSE: Information on the incidence of vascular disease in women of reproductive age has been limited. These disease are rare in this age group, and a large population base is required for reliable estimation of incidence.
METHODS: For a case-control study of vascular disease and low-dose oral contraceptive use, we used emergency department logs and hospital admission and discharge records to ascertain fatal and nonfatal cases of first-ever stroke and myocardial infarction (MI) in women 15 to 44 years of age who were-members of a large California HMO. Incidence rates of stroke and MI were calculated on the basis of these data.
RESULTS: The incidence of MI not associated with pregnancy was 5.0 per 100,000 women-years. The incidence of stroke not associated with pregnancy was 10.7 per 100,000 women-years. MI was very rare until age 35 years. At every age, about half of hemorrhagic strokes were due to subarachnoid hemorrhage.
CONCLUSIONS: The incidence rates of stroke and MI are low in women of reproductive age in the United States.
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Kaiser Permanente Medical Care Program, Southern California Region, USA.
PMID