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Antenatal depression: Pregnancy and neonatal outcomes

Sophie Grigoriadis, MD, MA, PhD, FRCPC
Section Editors
Peter P Roy-Byrne, MD
Charles J Lockwood, MD, MHCM
Deputy Editor
David Solomon, MD


Antenatal maternal depression is associated with adverse effects upon pregnancy and neonatal outcomes [1-3]. In addition, prenatal depression is associated with abnormal infant and child development, as well as cognitive problems and psychopathology in the offspring.

This topic reviews the association between antenatal depression and pregnancy and neonatal outcomes. The association of antenatal depression with abnormal child development, as well as cognitive impairment and psychopathology in the offspring, are discussed separately, as are the risks of prenatal antidepressants, and the clinical features, assessment, diagnosis, and treatment of antenatal depression:

(See "Antenatal depression: Risks of abnormal infant and child development".)

(See "Antenatal depression: Risks of cognitive impairment and psychopathology in the offspring".)

(See "Antenatal use of antidepressants and risk of teratogenicity and adverse pregnancy outcomes: Selective serotonin reuptake inhibitors (SSRIs)".)

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Literature review current through: Nov 2017. | This topic last updated: Feb 07, 2017.
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