Amoxicillin/Clavulanic Acid-Induced Agranulocytosis: A Case Report and Review of the Literature

Aristides Armas Villalba; Marya Haq; Cunxian Zhang; Jinen Thakkar

doi:10.1155/2019/5718716

Amoxicillin/Clavulanic Acid-Induced Agranulocytosis: A Case Report and Review of the Literature

Case Rep Hematol. 2019 Oct 23:2019:5718716. doi: 10.1155/2019/5718716. eCollection 2019.

Authors

Aristides Armas Villalba¹, Marya Haq¹, Cunxian Zhang^{2

3}, Jinen Thakkar¹

Affiliations

¹ Internal Medicine Department, Kent County Hospital, Warren Alpert Medical School of Brown University, Providence, RI, USA.
² Associate Professor of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA.
³ Chief of Pathology, Kent County Hospital, Warwick, RI, USA.

Abstract

Amoxicillin/clavulanic acid is one of the widely prescribed antibiotics in the outpatient setting giving excellent antimicrobial coverage and relatively safe profile in terms of adverse reactions. Gastrointestinal and cutaneous reactions are among the commonly reported. Our goal is to describe a case of agranulocytosis induced by amoxicillin/clavulanic acid in a previously healthy patient and review prior reports with similar presentation.

Publication types

Case Reports