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Adrenal hyperandrogenism

George P Chrousos, MD
Section Editor
André Lacroix, MD
Deputy Editor
Kathryn A Martin, MD


The adrenal glands are a prominent source of androgen, particularly in children and women. Excess adrenal androgen secretion occurs in several different patient groups:

It is a common and well-recognized cause of virilization in infants and children and an occasional cause of hirsutism and virilization in women. (See "Adrenal steroid biosynthesis" and "Pathophysiology and causes of hirsutism".)

It can occur in men, in whom it has few clinical manifestations.

It may contribute to the clinical findings in some patients with Cushing's syndrome. (See "Epidemiology and clinical manifestations of Cushing's syndrome".)

This topic will provide an overview of adrenal androgen synthesis and disorders associated with excess adrenal androgen secretion. More detailed discussions of individual disorders are found separately.

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Literature review current through: Nov 2017. | This topic last updated: Oct 31, 2016.
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