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Medline ® Abstract for Reference 40

of 'Acupuncture'

40
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Electroacupuncture treatment of morphine-dependent mice reduces signs of withdrawal, without showing cross-tolerance.
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Cheng RS, Pomeranz B, Yu G
SO
Eur J Pharmacol. 1980;68(4):477.
 
Morphine pellets (75 mg morphine base per pellet) were implanted subcutaneously in mice (B6AF1/J) and were surgically removed after 3 or 8 days. During morphine abstinence (7 h after pellet removal), the mice were treated with electroacupuncture (EA). The results indicate that EA analgesia shows no cross-tolerance to morphine. Additionally, EA reduced withdrawal behaviour (jumping) in 50% of the mice during morphine abstinence.
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PMID