Consult the medical resource doctors trust

UpToDate is one of the most respected medical information resources in the world, used by over 360,000 doctors and thousands of patients to find answers to medical questions.

  • Content written by a faculty of over 4,000 physicians from leading medical institutions
  • Unbiased: free of advertising or pharmaceutical funding
  • Evidence-based treatment recommendations
  • Continuously updated to incorporate new medical findings

Indications for and complications of central venous catheters

INTRODUCTION

Insertion of a central venous catheter (CVC) in a human was first reported by Werner Forssman, a surgical intern, who described canalizing his own right atrium via the cephalic vein in 1929. A technique that facilitates catheter placement into lumens and body cavities was subsequently introduced by Sven-Ivar Seldinger in 1953 [1]. Insertion of a CVC using the Seldinger technique has revolutionized medicine by allowing the central venous system to be accessed safely and easily [2].

CVCs are now common among critically ill patients. More than five million central lines are inserted each year in the United States alone [3]. Multi-lumen central venous catheters have become ubiquitous in the intensive care unit (ICU). New catheter designs and standardization of insertion techniques have reduced complication rates.

Indications, strategies to prevent complications, mechanical complications, and catheter removal are discussed here. The placement of CVCs and CVC-related infectious and thrombotic complications are discussed separately. (See "Placement of central venous catheters" and "Diagnosis of intravascular catheter-related infections" and "Prevention of intravascular catheter-related infections" and "Pathogenesis of and risk factors for central venous catheter-related infections" and "Catheter-induced upper extremity venous thrombosis".)

INDICATIONS

Common indications for placement of a CVC include:

  • Hemodynamic monitoring — A CVC permits measurement of the central venous pressure and the venous oxyhemoglobin saturation. In addition, it provides a conduit for insertion of a pulmonary artery catheter. (See "Insertion of Swan-Ganz catheters".)

To continue reading this article you need to subscribe.

Read the rest of this article and others like it

The content on the UpToDate website is not intended nor recommended as a substitute for medical advice, diagnosis, or treatment. Always seek the advice of your own physician or other qualified health care professional regarding any medical questions or conditions. The use of this website is governed by the UpToDate Terms of Use (click here) ©2010 UpToDate, Inc.
References Top
  1. Seldinger, SI. Catheter replacement of the needle in percutaneous arteriography; a new technique. Acta radiol 1953; 39:368.
  2. Higgs, ZC, Macafee, DA, Braithwaite, BD, Maxwell-Armstrong, CA. The Seldinger technique: 50 years on. Lancet 2005; 366:1407.
  3. Kondro, W. Alberta retreats over sterilisation compensation. Lancet 1998; 351:892.
  4. Graber, D, Dailey, RH. Catheter flow rates updated. JACEP 1977; 6:518.
  5. Pronovost, P, Needham, D, Berenholtz, S, et al. An intervention to decrease catheter-related bloodstream infections in the ICU. N Engl J Med 2006; 355:2725.
  6. Chaiyakunapruk, N, Veenstra, DL, Lipsky, BA, Saint, S. Chlorhexidine compared with povidone-iodine solution for vascular catheter-site care: a meta-analysis. Ann Intern Med 2002; 136:792.
  7. Merrer, J, Jonghe, BD, Golliot, F, et al. Complications of femoral and subclavian venous catheterization in critically ill patients. A randomized controlled trial. JAMA 2001; 286:700.
  8. Veenstra, DL, Saint, S, Saha, S, et al. Efficacy of antiseptic-impregnated central venous catheters in preventing catheter-related bloodstream infection: a meta-analysis. JAMA 1999; 281:261.
  9. Kalfon, P, de Vaumas, C, Samba, D, et al. Comparison of silver-impregnated with standard multi-lumen central venous catheters in critically ill patients. Crit Care Med 2007; 35:1032.
  10. Berenholtz, SM, Pronovost, PJ, Lipsett, PA, et al. Eliminating catheter-related bloodstream infections in the intensive care unit. Crit Care Med 2004; 32:2014.
  11. Shapey, IM, Foster, MA, Whitehouse, T, et al. Central venous catheter-related bloodstream infections: improving post-insertion catheter care. J Hosp Infect 2009; 71:117.
  12. Sznajder, JI, Zveibil, FR, Bitterman, H, et al. Central vein catheterization. Failure and complication rates by three percutaneous approaches. Arch Intern Med 1986; 146:259.
  13. Ramakrishna, G, Higano, ST, McDonald, FS, Schultz, HJ. A curricular initiative for internal medicine residents to enhance proficiency in internal jugular central venous line placement. Mayo Clin Proc 2005; 80:212.
  14. Mansfield, PF, Hohn, DC, Fornage, BD, et al. Complications and failures of subclavian-vein catheterization. N Engl J Med 1994; 331:1735.
  15. Britt, RC, Novosel, TJ, Britt, LD, Sullivan, M. The impact of central line simulation before the ICU experience. Am J Surg 2009; 197:533.
  16. Hilty, WM, Hudson, PA, Levitt, MA, Hall, JB. Real-time ultrasound-guided femoral vein catheterization during cardiopulmonary resuscitation. Ann Emerg Med 1997; 29:331.
  17. Calvert, N, Hind, D, McWilliams, R, et al. Ultrasound for central venous cannulation: economic evaluation of cost-effectiveness. Anaesthesia 2004; 59:1116.
  18. Hind, D, Calvert, N, McWilliams, R, et al. Ultrasonic locating devices for central venous cannulation: meta-analysis. BMJ 2003; 327:361.
  19. Randolph, AG, Cook, DJ, Gonzales, CA. Pribble, CG. Ultrasound guidance for placement of central venous catheters: A meta-analysis of literature. Crit Care Med 1996; 24:2053.
  20. Armstrong, PJ, Cullen, M, Scott, DH. The "siterite" ultrasound machine - an aid to internal jugular vein cannulation. Anaesthesia 1993; 48:319.
  21. Gordon, AC, Saliken, JC, Johns, D, et al. US-guided puncture of the internal jugular vein: Complications and anatomic considerations. J Vasc Interv Radiol 1998; 9:333.
  22. Caridi, JG, Hawkins, IF Jr, Wiechmann, BN, et al. Sonographic guidance when using the right internal jugular vein for central vein access. AJR Am J Roentgenol 1998; 171:1259.
  23. Fry, WR, Clagett, GC, O'Rourke, PT. Ultrasound-guided central venous access. Arch Surg 1999; 134:738.
  24. Lefrant, JY, Cuvillon, P, Benezet, JF, et al. Pulsed Doppler ultrasonography guidance for catheterization of the subclavian vein: a randomized study. Anesthesiology 1998; 88:1195.
  25. Blitt, CD. Monitoring in anesthesia and critical care medicine. Churchill Livingstone, New York 1990.p.204.
  26. Abood, GJ, Davis, KA, Esposito, TJ, et al. Comparison of routine chest radiograph versus clinician judgment to determine adequate central line placement in critically ill patients. J Trauma 2007; 63:50.
  27. Gebhard, RE, Szmuk, P, Pivalizza, EG, et al. The accuracy of electrocardiogram-controlled central line placement. Anesth Analg 2007; 104:65.
  28. McGee, DC, Gould, MK. Preventing complications of central venous catheterization. N Engl J Med 2003; 348:1123.
  29. Eisen, LA, Narasimhan, M, Berger, JS, et al. Mechanical complications of central venous catheters. J Intensive Care Med 2006; 21:40.
  30. Boyd, R, Saxe, A, Phillips, E. Effect of patient position upon success in placing central venous catheters. Am J Surg 1996; 172:380.
  31. Tripathi, M, Dubey, PK, Ambesh, SP. Direction of the J-tip of the guidewire, in seldinger technique, is a significant factor in misplacement of subclavian vein catheter: a randomized, controlled study. Anesth Analg 2005; 100:21.
  32. Lefrant, JY, Muller, L, De La, Coussaye JE, et al. Risk factors of failure and immediate complication of subclavian vein catheterization in critically ill patients. Intensive Care Med 2002; 28:1036.
  33. Jobes, DR, Schwartz, AJ, Greenhow, DE, et al. Safer jugular vein cannulation: recognition of arterial puncture and preferential use of the external jugular route. Anesthesiology 1983; 59:353.
  34. Oliver, WC Jr, Nuttall, GA, Beynen, FM, et al. The incidence of artery puncture with central venous cannulation using a modified technique for detection and prevention of arterial cannulation. J Cardiothorac Vasc Anesth 1997; 11:851.
  35. Mirski, MA, Lele, AV, Fitzsimmons, L, Toung, TJ. Diagnosis and treatment of vascular air embolism. Anesthesiology 2007; 106:164.
  36. Flanagan, JP, Gradisar, IA, Gross, RJ, Kelly, TR. Air embolus--a lethal complication of subclavian venipuncture. N Engl J Med 1969; 281:488.
  37. Toung, TJ, Rossberg, MI, Hutchins, GM. Volume of air in a lethal venous air embolism. Anesthesiology 2001; 94:360.
  38. Ely, EW, Hite, RD, Baker, AM, et al. Venous air embolism from central venous catheterization: a need for increased physician awareness. Crit Care Med 1999; 27:2113.
  39. Roberts, S, Johnson, M, Davies, S. Near-fatal air embolism: fibrin sheath as the portal of air entry. South Med J 2003; 96:1036.
  40. Laskey, AL, Dyer, C, Tobias, JD. Venous air embolism during home infusion therapy. Pediatrics 2002; 109:E15.
  41. Heckmann, JG, Lang, CJ, Kindler, K, et al. Neurologic manifestations of cerebral air embolism as a complication of central venous catheterization. Crit Care Med 2000; 28:1621.
white circle LOG IN
white circle DEMO