Consult the medical resource doctors trust

UpToDate is one of the most respected medical information resources in the world, used by over 360,000 doctors and thousands of patients to find answers to medical questions.

  • Content written by a faculty of over 4,000 physicians from leading medical institutions
  • Unbiased: free of advertising or pharmaceutical funding
  • Evidence-based treatment recommendations
  • Continuously updated to incorporate new medical findings

Related articles included with a subscription

Preview Available
(subscription required for full access)

Cerumen

INTRODUCTION

Ear wax, or cerumen, is a hydrophobic protective covering in the ear canal. It acts to protect the skin of the external canal from water damage, infection, trauma, and traps foreign particles and aids in elimination of bacteria [1,2]. The formation of cerumen and indications for and techniques of removal are reviewed here.

ANATOMY OF THE EXTERNAL AUDITORY CANAL

Cerumen is found in the external auditory canal (EAC), which begins at the meatus of the auricle. The EAC consists of hair and glandular-bearing skin on top of fibrocartilaginous tissue for the first lateral one-third (figure 1). The appendages of the skin at the lateral third of the EAC are responsible for the components of cerumen. The skin then becomes thin and adherent to the periosteum of the temporal bone for the medial two-thirds of the canal. The canal narrows in most individuals at the junction of the bony and fibrocartilaginous portions of the canal and again more significantly at the isthmus in the mid-portion of the bony canal. Cerumen trapped medial to the isthmus tends to become impacted and cause hearing loss.

At the most medial end of the external canal is the tympanic membrane. The lateral layer of the tympanic membrane consists of keratinizing squamous epithelium that is in continuity with the epithelium of the external canal [3,4]. (See "External otitis", for further descriptions of the ear canal and its relationship to external ear canal disease).

COMPOSITION AND APPEARANCE

Cerumen is composed of the secretions of both sebaceous and cerumenous glands located in the lateral one-third of the external ear canal. These secretions mix with desquamated skin, the bacteria of normal skin flora, and occasional depilated hair to form cerumen [5-7]. Water trapped in the ear canal also mixes with cerumen.

Cerumen has a wide range of appearance from almost liquid to rock hard, depending upon the percentage of its different components, time spent in the ear canal (harder cerumen has been present longer), and the amount of desquamated skin. Color ranges from a deep, dark red that can appear black, to off-white. A given individual may have different color cerumen in each ear. The color of the cerumen reflects its composition, but does not necessarily depict normalcy or the health of the external canal. Harder cerumen has an increased tendency to accumulate but does not warrant removal unless there is a specific otologic complaint (see below).

To continue reading this article you need to subscribe.

Read the rest of this article and others like it

The content on the UpToDate website is not intended nor recommended as a substitute for medical advice, diagnosis, or treatment. Always seek the advice of your own physician or other qualified health care professional regarding any medical questions or conditions. The use of this website is governed by the UpToDate Terms of Use (click here) ©2009 UpToDate, Inc.
References Top
  1. Kelly, KE, Mohs, DC. The external auditory canal. Anatomy and physiology. Otolaryngol Clin North Am 1996; 29:725.
  2. Jabor, MA, Amedee, RG. Cerumen impaction. J La State Med Soc 1997; 149:358.
  3. Donaldson, JA, Duckert, LG. Anatomy of the Ear. In: Otolaryngology, 3rd ed, Paparella, MM, Shumrick, DA, Gluckman, JL, Meyerhoff, WL (Eds), WB Saunders, Philadelphia 1991. p.23.
  4. Litton, WB. Epithelial migration over tympanic membrane and external canal. Arch Otolaryngol 1963; 77:254.
  5. Campos, A, Arias, A, Betancor, L, et al. Study of common aerobic flora of human cerumen. J Laryngol Otol 1998; 112:613.
  6. Burkhart, CN, Burkhart, CG, Williams, S, et al. In pursuit of ceruminolytic agents: a study of earwax composition. Am J Otol 2000; 21:157.
  7. Guest, JF, Greener, MJ, Robinson, AC, Smith, AF. Impacted cerumen: composition, production, epidemiology and management. QJM 2004; 97:477.
  8. Meador, JA. Cerumen impaction in the elderly. J Gerontol Nurs 1995; 21:43.
  9. Roland, PS, Smith, TL, Schwartz, SR, et al. Clinical practice guideline: cerumen impaction. Otolaryngol Head Neck Surg 2008; 139 (2 suppl):S1.
  10. Burton, JH, Doree, CJ. Ear drops for the removal or ear wax. Cochrane Database Syst Rev 2003; :CD004326.
  11. Keane, EM, Wilson, H, McGrane, D, et al. Use of solvents to disperse ear wax. Br J Clin Pract 1995; 49:71.
  12. Singer, AJ, Sauris, E, Viccellio, AW. Ceruminolytic effects of docusate sodium: a randomized, controlled trial. Ann Emerg Med 2000; 36:228.
  13. Amjad, AH, Scheer, AA. Clinical evaluation of ceruminolytic agents. Eye Ear Nose Throat Mon 1975; 54?:76.
  14. Chaput de, Saintonge DM, Johnstone, CI. A clinical comparison of triethanolamine polypeptide oleate-condensate ear drops with olive oil for the removal of impacted wax. Br J Clin Pract 1973; 27:454.
  15. Fraser, JG. The efficacy of wax solvents: in vitro studies and a clinical trial. J Laryngol Otol 1970; 84:1055.
  16. Roland, PS, Eaton, DA, Gross, RD, et al. Randomized, placebo-controlled evaluation of Cerumenex and Murine earwax removal products. Arch Otolaryngol Head Neck Surg 2004; 130:1175.
  17. Dummer, DS, Sutherland, IA, Murray, JA. A single-blind, randomized study to compare the efficacy of two ear drop preparations ('Audax' and 'Cerumol') in the softening of ear wax. Curr Med Res Opin 1992; 13:26.
  18. Lyndon, S, Roy, P, Grillage, MG, Miller, AJ. A comparison of the efficacy of two ear drop preparations ('Audax' and 'Earex') in the softening and removal of impacted ear wax. Curr Med Res Opin 1992; 13:21.
  19. Fahmy, S, Whitefield, M. Multicentre clinical trial of Exterol as a cerumenolytic. Br J Clin Pract 1982; 36:197.
  20. Jaffe, G, Grimshaw, J. A multicentric clinical trial comparing Otocerol with Cerumol as cerumenolytics. J Int Med Res 1978; 6:241.
  21. Dinsdale, RC, Roland, PS, Manning, SC, Meyerhoff, WL. Catastrophic otologic injury from oral jet irrigation of the external auditory canal. Laryngoscope 1991; 101:75.
  22. Sorensen, VZ, Bonding, P. Can ear irrigation cause rupture of the normal tympanic membrane?: an experimental study in man. J Laryngol Otol 1995; 109:1036.
  23. Sharp, JF, Wilson, JA, Ross, L, Barr-Hamilton, RM. Ear wax removal: a survey of current practice. BMJ 1990; 301:1251.
  24. Food and Drug Administration. Detention without physical examination of ear candles. www.fda.gov/ora/fiars/ora_import_ia7701.html (Accessed October 14, 2008).
  25. Saloranta, K, Westermarck, T. Prevention of cerumen impaction by treatment of ear canal skin. A pilot randomized controlled study. Clin Otolaryngol 2005; 30:112.
white circle LOG IN
white circle DEMO