Since January 2004, relative search interest associated with UpToDate has increased steadily, whereas web-based queries for other sources of online medical information have declined (Figure 1).
Relative search interest in UpToDate has, on average, exceeded that of JAMA, NEJM, and PDR since approximately July 2011 (Figure 1), whereas PubMed has been associated with the greatest, albeit diminishing, relative search interest.
Linear regression yielded the following significant (P < 0.001) coefficients of trend for UpToDate (coefficient = 0.010), JAMA (coefficient = −0.012), NEJM (coefficient = −0.030), PDR (coefficient = −0.020), and PubMed (coefficient = −0.011). Every coefficient differed significantly from each other (P < 0.001).
Google Search trends for online medical information. Temporal trends in relative Google search query interest by online medical resource, 2004 to 2013. Abbreviations: JAMA, Journal of the American Medical Association; NEJM, New England Journal of Medicine; PDR, Physicians' Desk Reference.