Clinical Podcasts

UpToDate faculty discuss important “What’s New” and “Practice Changing UpDates”, based on recent medical journal articles, in our clinical podcasts. Our contributors are recognized physician leaders in their fields and offer their expertise regarding each update and its impact on clinical practice. Each clinical podcast includes the most current clinical information available as of the release date listed.

Support for UpToDate Talk is provided by UpToDate, Wolters Kluwer. UpToDate is entirely funded by the subscriptions of its users and does not accept advertising or funding unrelated to subscriptions. The opinions in such podcasts are entirely those of the discussants, and these discussants are authors and editors for UpToDate. View the UpToDate conflict of interest policy.

To be alerted as each new episode airs, simply subscribe to our podcast channel on iTunes. Also, check out our Healthcare Industry Podcasts that explore healthcare initiatives with an impact on quality and patient safety. We hope you will find these series an enjoyable way to keep UpToDate!

Severe asymptomatic hypertension; Endovascular vs. open abdominal aneurysm repair

Date Released: Jan 25 2017

In this episode, Dr. William Elliott discusses management of hypertensive urgency (starts at 00:50); and Dr. John Eidt discusses a comparison of long-term outcomes following endovascular and open surgical repair of an asymptomatic abdominal aneurysm (starts at 17:09). Dr. Nancy Sokol hosts.

Listen to the full podcast by pressing the Play Button below, or jump to the segment on severe asymptomatic hypertension, or the segment on endovascular vs. open abdominal aneurysm repair.

Dr. ElliottDr. William Elliott is a Professor of Preventive Medicine and Internal Medicine and Chair of the Department of Biomedical Sciences at the Pacific Northwest University of Health Science in Washington State.
Dr. EidtDr. John Eidt is a Professor of Surgery at Texas A&M Health Science Center and Vice Chair of Surgery at Baylor University Medical Center in Dallas, TX.

Segment on severe asymptomatic hypertension (Dr. Elliott):

  1. Patel KK, Young L, Howell EH, et al. Characteristics and Outcomes of Patients Presenting With Hypertensive Urgency in the Office Setting. JAMA Intern Med 2016; 176:981.

Segment on endovascular vs. open abdominal aneurysm repair (Dr. Eidt):

  1. Patel R, Sweeting MJ, Powell JT, et al. Endovascular versus open repair of abdominal aortic aneurysm in 15-years' follow-up of the UK endovascular aneurysm repair trial 1 (EVAR trial 1): a randomised controlled trial. Lancet 2016; 388:2366.

William J Elliott, MD, PhD Consultant/Advisory Board: Novartis [Hypertension]. Other Financial Interest: Elsevier; Springer [Hypertension (book, journal)].

John F Eidt, MD Nothing to disclose

Overdiagnosis of breast cancer with mammography

Date Released: Jan 12 2017

This episode features Dr. Joann Elmore, discussing the UpToDate What’s New topic on the overdiagnosis of breast cancer with mammography. Dr. Sandy Falk hosts.

Dr. ElmoreDr. Joann Elmore is a Professor of Medicine at the University of Washington School of Medicine.

Segment on overdiagnosis of breast cancer with mammography (Dr. Elmore):

  1. Welch HG, Prorok PC, O'Malley AJ, Kramer BS. Breast-Cancer Tumor Size, Overdiagnosis, and Mammography Screening Effectiveness. N Engl J Med 2016; 375:1438.


Joann G Elmore, MD, MPH Nothing to disclose


Glucocorticoids and sepsis; HPV vaccination in young adolescents

Date Released: Dec 21 2016

This episode features Dr. Scott Manaker, discussing the UpToDate What’s New topic on the lack of benefit of glucocorticoids in severe sepsis (starts at 01:07); and Dr. Joel Palefsky, discussing the UpToDate Practice Changing UpDate regarding updated guidelines for HPV vaccination in young adolescents (starts at 14:56). Dr. Sandy Falk hosts.

Listen to the full podcast by pressing the Play Button below, or jump to the segment on glucocorticoids and sepsis, or the segment on HPV vaccination in young adolescents.

Dr. ManakerDr. Scott Manaker is Professor of Medicine at the University of Pennsylvania School of Medicine and an actively practicing physician in pulmonary and critical care medicine.
Dr. PalefskyDr. Joel Palefsky is a Professor of Medicine and an Infectious Disease Specialist at the University of California San Francisco, and the chair of the HPV working group of the National Cancer Institute, AIDS Malignancy Consortia.

Segment on glucocorticoids and sepsis (Dr. Manaker):

  1. Keh D, Trips E, Marx G, et al. Effect of Hydrocortisone on Development of Shock Among Patients With Severe Sepsis: The HYPRESS Randomized Clinical Trial. JAMA 2016; 316:1775.

HPV vaccination in young adolescents (Dr. Palefsky):

  1. CDC recommends only two HPV shots for younger adolescents, October 19, 2016. (Accessed on October 22, 2016).


Scott Manaker, MD, PhD Consultant/Advisory boards: Expert witness in workers' compensation and in medical negligence matters [General pulmonary and critical care medicine]. Equity Ownership/Stock Options (Spouse): Johnson & Johnson; Pfizer (Numerous medications and devices). Other Financial Interest: Director of ACCP Enterprises, a wholly owned for-profit subsidiary of ACCP [General pulmonary and critical care medicine (Providing pulmonary and critical care medicine education to non-members of ACCP)].

Joel M Palefsky, MD Grant/Research/Clinical Trial Support: Merck and Co [HPV vaccine (Gardasil-9)]. Consultant/Advisory Boards: TheVax [HPV infection (therapeutic HPV vaccine)]; Ubiome [HPV diagnostics (none)]. Equity Ownership/Stock Options: Antiva Therapeutics [HPV therapeutics (none)]; Agenovir Corporation HPV therapeutics (none)].


Influenza vaccination in pregnancy; Degenerative meniscal tears

Date Released: Dec 7 2016

This episode features Dr. Sonja Rasmussen, discussing infant protection against influenza illness through maternal immunization (starts at 00:44); and Dr. Karl Fields, discussing outcomes for patients with degenerative meniscal tears, comparing meniscectomy with physical therapy (starts at 13:38). Dr. Nancy Sokol hosts.

Listen to the full podcast by pressing the Play Button below, or jump to the segment on influenza and pregnancy or the segment on degenerative meniscal tears.

Dr. RasmussenDr. Sonja Rasmussen is the Director of the Division of Public Health Information Dissemination at the Centers for Disease Control and Prevention, and Editor in Chief of CDC's Morbidity and Mortality Weekly Report, MMWR.
Dr. FieldsDr. Karl Fields is Professor of Family Medicine at the University of North Carolina Medical School in Chapel Hill and is Past President of the American Medical Society of Sports Medicine.

Segment on influenza and pregnancy (Dr. Rasmussen):

  1. Nunes MC, Cutland CL, Jones S, et al. Duration of Infant Protection Against Influenza Illness Conferred by Maternal Immunization: Secondary Analysis of a Randomized Clinical Trial. JAMA Pediatr 2016; 170:840.

Segment on degenerative meniscal tears (Dr. Fields):

  1. Kise NJ, Risberg MA, Stensrud S, et al. Exercise therapy versus arthroscopic partial meniscectomy for degenerative meniscal tear in middle aged patients: randomised controlled trial with two year follow-up. BMJ 2016; 354:i3740.


Sonja A Rasmussen, MD, MS Nothing to disclose

Karl B Fields, MD Nothing to disclose