Medline ® Abstract for Reference 113
of 'Zika virus infection: An overview'
Characteristics of Children Aged<18 Years with Zika Virus Disease Acquired Postnatally - U.S. States, January 2015-July 2016.
Goodman AB, Dziuban EJ, Powell K, Bitsko RH, Langley G, Lindsey N, Franks JL, Russell K, Dasgupta S, Barfield WD, Odom E, Kahn E, Martin S, Fischer M, Staples JE
MMWR Morb Mortal Wkly Rep. 2016;65(39):1082. Epub 2016 Oct 7.
Zika virus is an emerging mosquito-borne flavivirus that typically causes an asymptomatic infection or mild illness, although infection during pregnancy is a cause of microcephaly and other serious brain abnormalities. Guillain-Barrésyndrome and other neurologic complications can occur in adults after Zika virus infection. However, there are few published reports describing postnatally acquired Zika virus disease among children. During January 2015-July 2016, a total of 158 cases of confirmed or probable postnatally acquired Zika virus disease among children aged<18 years were reported to CDC from U.S. states. The median age was 14 years (range = 1 month-17 years), and 88 (56%) were female. Two (1%) patients were hospitalized; none developed Guillain-Barrésyndrome, and none died. All reported cases were travel-associated. Overall, 129 (82%) children had rash, 87 (55%) had fever, 45 (29%) had conjunctivitis, and 44 (28%) had arthralgia. Health care providers should consider a diagnosis of Zika virus disease in children who have an epidemiologic risk factor and clinically compatible illness, and should report cases to their state or local health department.