成人无并发症胆石病
- Author
- Salam F Zakko, MD, FACP
Salam F Zakko, MD, FACP
- Executive Director, Connecticut Gastroenterology Institute
- Clinical Professor of Medicine, University of Connecticut School of Medicine
- Section Editor
- Sanjiv Chopra, MD, MACP
Sanjiv Chopra, MD, MACP
- Editor-in-Chief — Gastroenterology/Hepatology
- Section Editor — General Hepatology; Gallbladder and Biliary Tract Disease
- Professor of Medicine
- Harvard Medical School
- Senior Consultant in Hepatology
- James Tullis Firm Chief
- Beth Israel Deaconess Medical Center
- Deputy Editor
- Anne C Travis, MD, MSc, FACG, AGAF
Anne C Travis, MD, MSc, FACG, AGAF
- Deputy Editor — Gastroenterology/Hepatology
- Assistant Professor of Medicine, Part-time
- Harvard Medical School
引言
胆石常见,尤其是在西方人群中(表 1)。在美国,胆石可见于约6%的男性以及9%的女性。大多数胆石患者终其一生都没有症状。当胆石开始引发症状,被称为胆石病。无并发症胆石病是指胆囊结石引起胆绞痛,但不伴急性胆囊炎、胆管炎或胆石性胰腺炎等并发症。
很难明确患者的上消化道症状是否为影像学检查到的胆石引起。在普通人群中,虽然胆石和上消化道症状很常见,但是这二者并不总是相关。对无并发症胆石病与其他疾病中偶然发现的胆石进行鉴别极为重要,因为胆囊切除术对有症状的胆石往往能治愈,但也使那些偶发胆石的患者承受不必要的风险,延误了对该症状真实病因的适当治疗,并导致不必要的医疗费用。
本专题将总结无并发症胆石病。胆石流行病学、危险因素、偶然发现胆石患者的处理方法、妊娠期妇女胆石病,以及胆石病并发症将单独讨论。 (参见“胆石症的流行病学和危险因素”和“意外发现胆结石的概述”和“妊娠期胆石症”和“急性胆囊炎的发病机制、临床特征和诊断”和“急性胰腺炎的病因”,关于‘胆石’一节和“急性胆管炎”和“胆总管结石:临床表现、诊断和处理”)
接下来的讨论与英国国家卫生与保健评价研究院的指南基本一致[1]。
患者分类
当考虑胆石病时,我们发现将患者分为如下临床组是有帮助的:
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Topic Outline
- 引言
- 患者分类
- 自然病程
- 临床特征
- 胆绞痛
- 非典型症状
- 体格检查
- 实验室检查
- 影像学检查
- 诊断
- 经腹超声
- - 胆石超声特征
- - 检查特征
- 超声结果阴性的下一步处理
- - 一般处理方法
- - 腹部超声复查
- - 超声内镜
- - 胆汁显微镜检查
- 胆汁收集
- 极少进行的检查
- - 口服法胆囊造影
- 鉴别诊断
- 上腹部症状
- 胆源性疼痛的其他疾病
- - 急性胆囊炎
- - 胆总管结石病
- - Oddi括约肌功能障碍
- - 功能性胆囊病
- 治疗
- 第一类患者(有胆石但无症状)
- 第二类患者(有典型胆道系统症状且发现有胆石)
- - 疼痛处理
- - 胆囊切除术
- 手术方法
- 疗效
- 并发症和副作用
- 胆囊切除术的替代治疗
- 第三类患者(有胆石但症状不典型)
- 第四类患者(有典型胆道系统症状但超声未发现胆石)
- 胆石相关并发症患者
- 妊娠女性胆石
- 患者教育
- 总结与推荐
- REFERENCES
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