经阴道超声评估宫颈与预测自发性早产
- Author
- Vincenzo Berghella, MD
Vincenzo Berghella, MD
- Section Editor — Obstetrics
- Director, Maternal-Fetal Medicine
- Professor, Obstetrics and Gynecology
- Thomas Jefferson University
- Section Editors
- Charles J Lockwood, MD, MHCM
Charles J Lockwood, MD, MHCM
- Section Editor — Obstetrics
- Senior Vice President, USF Health
- Dean, Morsani College of Medicine
- Professor, Obstetrics and Gynecology
- University of South Florida
- Deborah Levine, MD
Deborah Levine, MD
- Section Editor — Imaging
- Professor of Radiology
- Director of Ob/Gyn Ultrasound
- Department of Radiology
- Beth Israel Deaconess Medical Center
- Deputy Editor
- Vanessa A Barss, MD, FACOG
Vanessa A Barss, MD, FACOG
- Senior Deputy Editor — UpToDate
- Deputy Editor — Obstetrics, Gynecology and Women's Health
- Associate Clinical Professor of Obstetrics, Gynecology and Reproductive Biology
- Harvard Medical School
- Translators
- 熊奕, 主任医师
熊奕, 主任医师
- 深圳市人民医院超声科
引言
妊娠期宫颈超声成像促进了我们对于妊娠期宫颈功能的理解。宫颈管消退是分娩过程的第一步,至少比临产早4-8周。宫颈管消退首先发生在宫颈内口,朝尾侧方向依次消退,所以经超声可见,但通过指检或视检并不一定能发现。随着妊娠中期宫颈长度缩短,自发性早产的风险增加[1-5],特别是当中期妊娠早期发生宫颈管消退时[6]。
尽管短宫颈可被视为分娩过程已开始的证据,但早产宫颈管缩短的原因常不明确。已提出的原因包括生物变异、隐匿性子宫活动、子宫过度扩张、先天性或获得性宫颈功能不全、蜕膜出血,以及感染或炎症。短宫颈和宫颈功能不全的危险因素将单独讨论。 (参见“宫颈机能不全”)
技术
经阴道超声(transvaginal ultrasound, TVU)检查是评估宫颈的重复性最好和最可靠的技术[7]。如果在妊娠25周以前行经腹超声检查怀疑有短宫颈,则应行TVU检查以获得宫颈长度的最佳估测。宫颈的经腹超声图像的重复性较差,因此不应用于临床处理[8-10]。
与TVU相比,经会阴超声更困难、重复性更差,且效度更差[11,12]。
时机 — 妊娠14周前测量宫颈长度的临床价值有限[13,14]。然而,对于某些特别高危的妊娠,例如曾发生妊娠中期胎儿丢失和/或行大的(或多次)宫颈锥切活检,可早在妊娠10-13周即观察到宫颈缩短,这时的宫颈缩短属于异常,会增加中期妊娠胎儿丢失的风险[13]。在妊娠约14周时,宫颈正常情况下与子宫下段有明显区别,这时宫颈长度测量可能具有可重复性。
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