Medline ® Abstract for Reference 9
Death related to midazolam overdose during endoscopic retrograde cholangiopancreatography.
Michalodimitrakis M, Christodoulou P, Tsatsakis AM, Askoxilakis I, Stiakakis I, Mouzas I
Am J Forensic Med Pathol. 1999;20(1):93.
We report a midazolam-related death that occurred during endoscopic retrograde cholangiopancreatography (ERCP). The acute intoxication due to midazolam overdose was confirmed by high-pressure liquid chromatography (HPLC) analysis of the blood samples taken from the patient in the intensive care unit (2.8 microg/ml) and postmortem (2.4 microg/ml). The case strongly emphasizes the necessity of the precautions that should be taken when midazolam is intravenously administered.
Department of Forensic Pathology, University of Crete, Iraklion, Greece.