免疫抑制剂和改变病情药物在风湿性疾病中的应用概述
- Author
- Philip Seo, MD
Philip Seo, MD
- Assistant Professor of Medicine
- Johns Hopkins University School of Medicine
- Section Editor
- Daniel E Furst, MD
Daniel E Furst, MD
- Section Editor — Treatment Issues in Rheumatology
- Clinical professor, University of Washington, Seattle
- Clinical professor, University of Florence, Florence, Italy
- Professor of Rheumatology, University of California in Los Angeles (Emeritus)
- Director of Research, Pacific Arthritis Associates
- Deputy Editor
- Paul L Romain, MD
Paul L Romain, MD
- Deputy Editor — Rheumatology
- Assistant Professor of Medicine, Part-time
- Harvard Medical School
- Translators
- 吴敏, 主任医师
吴敏, 主任医师
- 苏州大学附属第三医院常州市第一人民医风湿免疫科
引言
除糖皮质激素以外的免疫抑制剂被用于多种风湿性疾病的治疗,以达到以下一个或多个目标:
●诱导或维持缓解
●降低疾病发作或复发频率
●在维持疾病控制的同时允许糖皮质激素逐渐减量
本专题将概述免疫抑制剂在多种风湿性疾病中的应用。这些药物用于特定风湿性疾病的详细讨论请参见相应专题。
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- Adu D, Cross J, Jayne DR. Treatment of systemic lupus erythematosus with mycophenolate mofetil. Lupus 2001; 10:203.
- Sanders S, Harisdangkul V. Leflunomide for the treatment of rheumatoid arthritis and autoimmunity. Am J Med Sci 2002; 323:190.
- Guidelines for monitoring drug therapy in rheumatoid arthritis. American College of Rheumatology Ad Hoc Committee on Clinical Guidelines. Arthritis Rheum 1996; 39:723.
- van der Heide A, Jacobs JW, Bijlsma JW, et al. The effectiveness of early treatment with "second-line" antirheumatic drugs. A randomized, controlled trial. Ann Intern Med 1996; 124:699.
- ten Wolde S, Breedveld FC, Hermans J, et al. Randomised placebo-controlled study of stopping second-line drugs in rheumatoid arthritis. Lancet 1996; 347:347.
- Navarra SV, Guzmán RM, Gallacher AE, et al. Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial. Lancet 2011; 377:721.
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