CT结肠成像概述
- Author
- Stephan Anderson, MD
Stephan Anderson, MD
- Professor of Radiology
- Boston University School of Medicine
- Section Editors
- Kenneth K Tanabe, MD
Kenneth K Tanabe, MD
- Section Editor — Gastrointestinal Malignancies
- Professor of Surgery
- Harvard Medical School
- Jonathan B Kruskal, MD, PhD
Jonathan B Kruskal, MD, PhD
- Section Editor — Kidney Disease
- Professor of Radiology
- Harvard Medical School
- Deputy Editor
- Shilpa Grover, MD, MPH, AGAF
Shilpa Grover, MD, MPH, AGAF
- Deputy Editor — Gastroenterology/Hepatology
- Assistant Professor of Medicine, Part-time
- Harvard Medical School
- Translators
- 李军, 副主任医师
李军, 副主任医师
- 北京大学第三医院消化科
引言
CT结肠成像(CT colonography或CT colography)也称仿真结肠镜,对充气膨胀的结肠进行计算机腔内虚拟成像[1]。该技术通过常规螺旋CT扫描图像获得不间断的数据集,使用复杂的后处理软件成像,使操作者能够从所选择的任意方向评估清洁后的结肠。
本专题将总结CT结肠成像的准备、技术要点和风险。CT结肠成像在结直肠癌(colorectal cancer, CRC)筛查和诊断中的有效性将会单独详细讨论。 (参见“结直肠癌的临床表现、诊断和分期”,关于‘CT结肠成像’一节和“结直肠癌的筛查:粪便检测、放射影像学及内镜检查”)
患者选择
适应证 — CT结肠成像的可能适应证包括:
●CRC筛查–CT结肠成像是50岁以上无症状的平均风险个体的一种CRC筛查方法[2,3]。然而,CT结肠成像在筛查CRC中的作用是有争议的。虽然已经达成共识认为CT结肠成像检查不应该用于CRC高危人群的筛查(例如,有腺瘤、炎症性肠病、家族性CRC综合征病史的患者),但是不同的指南对平均风险患者接受CT结肠成像筛查的推荐不同。CRC筛查指南将会单独详细讨论。 (参见“结直肠癌筛查:一般风险人群的筛查策略”,关于‘一般风险的筛查指南’一节)
●评估同时性CRC–在CRC患者中,若因结肠镜无法通过肿瘤阻塞段而不能进行完整的结肠镜检查,CT结肠成像可排除近端同时性CRC。 (参见“结直肠癌筛查:一般风险人群的筛查策略”,关于‘一般风险的筛查指南’一节)
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- Levin B, Lieberman DA, McFarland B, et al. Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology. Gastroenterology 2008; 134:1570.
- U.S. Preventive Services Task Force. Screening for colorectal cancer: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med 2008; 149:627.
- Chang KJ, Rekhi SS Jr, Anderson SW, Soto JA. Fluid tagging for CT colonography: effectiveness of a 2-hour iodinated oral preparation after incomplete optical colonoscopy. J Comput Assist Tomogr 2011; 35:91.
- Kim B, Park SH, Hong GS, et al. Iohexol versus diatrizoate for fecal/fluid tagging during CT colonography performed with cathartic preparation: comparison of examination quality. Eur Radiol 2015; 25:1561.
- Iannaccone R, Laghi A, Catalano C, et al. Computed tomographic colonography without cathartic preparation for the detection of colorectal polyps. Gastroenterology 2004; 127:1300.
- Callstrom MR, Johnson CD, Fletcher JG, et al. CT colonography without cathartic preparation: feasibility study. Radiology 2001; 219:693.
- Zalis ME, Hahn PF. Digital subtraction bowel cleansing in CT colonography. AJR Am J Roentgenol 2001; 176:646.
- Lefere PA, Gryspeerdt SS, Dewyspelaere J, et al. Dietary fecal tagging as a cleansing method before CT colonography: initial results polyp detection and patient acceptance. Radiology 2002; 224:393.
- Thomeer M, Carbone I, Bosmans H, et al. Stool tagging applied in thin-slice multidetector computed tomography colonography. J Comput Assist Tomogr 2003; 27:132.
- Zalis ME, Perumpillichira J, Del Frate C, Hahn PF. CT colonography: digital subtraction bowel cleansing with mucosal reconstruction initial observations. Radiology 2003; 226:911.
- Bielen D, Thomeer M, Vanbeckevoort D, et al. Dry preparation for virtual CT colonography with fecal tagging using water-soluble contrast medium: initial results. Eur Radiol 2003; 13:453.
- Chen D, Liang Z, Wax MR, et al. A novel approach to extract colon lumen from CT images for virtual colonoscopy. IEEE Trans Med Imaging 2000; 19:1220.
- Stoop EM, de Haan MC, de Wijkerslooth TR, et al. Participation and yield of colonoscopy versus non-cathartic CT colonography in population-based screening for colorectal cancer: a randomised controlled trial. Lancet Oncol 2012; 13:55.
- Summers RM, Yao J, Pickhardt PJ, et al. Computed tomographic virtual colonoscopy computer-aided polyp detection in a screening population. Gastroenterology 2005; 129:1832.
- Halligan S, Altman DG, Mallett S, et al. Computed tomographic colonography: assessment of radiologist performance with and without computer-aided detection. Gastroenterology 2006; 131:1690.
- Trilisky I, Wroblewski K, Vannier MW, et al. CT colonography with computer-aided detection: recognizing the causes of false-positive reader results. Radiographics 2014; 34:1885.
- Sosna J, Blachar A, Amitai M, et al. Colonic perforation at CT colonography: assessment of risk in a multicenter large cohort. Radiology 2006; 239:457.
- Burling D, Halligan S, Slater A, et al. Potentially serious adverse events at CT colonography in symptomatic patients: national survey of the United Kingdom. Radiology 2006; 239:464.
- Pickhardt PJ. Incidence of colonic perforation at CT colonography: review of existing data and implications for screening of asymptomatic adults. Radiology 2006; 239:313.
- Pendsé DA, Taylor SA. Complications of CT colonography: a review. Eur J Radiol 2013; 82:1159.
- Berrington de González A, Kim KP, Knudsen AB, et al. Radiation-related cancer risks from CT colonography screening: a risk-benefit analysis. AJR Am J Roentgenol 2011; 196:816.
- Boellaard TN, Venema HW, Streekstra GJ, Stoker J. Effective radiation dose in CT colonography: is there a downward trend? Acad Radiol 2012; 19:1127.
- Chang KJ, Caovan DB, Grand DJ, et al. Reducing radiation dose at CT colonography: decreasing tube voltage to 100 kVp. Radiology 2013; 266:791.
- Yamamura S, Oda S, Imuta M, et al. Reducing the Radiation Dose for CT Colonography: Effect of Low Tube Voltage and Iterative Reconstruction. Acad Radiol 2016; 23:155.
- Shen H, Liang D, Luo M, et al. Pilot study on image quality and radiation dose of CT colonography with adaptive iterative dose reduction three-dimensional. PLoS One 2015; 10:e0117116.
- Ginnerup Pedersen B, Rosenkilde M, Christiansen TE, Laurberg S. Extracolonic findings at computed tomography colonography are a challenge. Gut 2003; 52:1744.
- Pickhardt PJ, Hanson ME. Incidental adnexal masses detected at low-dose unenhanced CT in asymptomatic women age 50 and older: implications for clinical management and ovarian cancer screening. Radiology 2010; 257:144.
- Macari M, Nevsky G, Bonavita J, et al. CT colonography in senior versus nonsenior patients: extracolonic findings, recommendations for additional imaging, and polyp prevalence. Radiology 2011; 259:767.
- Kim YS, Kim N, Kim SY, et al. Extracolonic findings in an asymptomatic screening population undergoing intravenous contrast-enhanced computed tomography colonography. J Gastroenterol Hepatol 2008; 23:e49.
- Flicker MS, Tsoukas AT, Hazra A, Dachman AH. Economic impact of extracolonic findings at computed tomographic colonography. J Comput Assist Tomogr 2008; 32:497.
- Gluecker TM, Johnson CD, Wilson LA, et al. Extracolonic findings at CT colonography: evaluation of prevalence and cost in a screening population. Gastroenterology 2003; 124:911.
- Pickhardt PJ, Kim DH, Meiners RJ, et al. Colorectal and extracolonic cancers detected at screening CT colonography in 10,286 asymptomatic adults. Radiology 2010; 255:83.
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