成人细菌性脑膜炎的神经系统并发症
- Author
- Daniel J Sexton, MD
Daniel J Sexton, MD
- Editor-in-Chief — Infectious Diseases
- Section Editor — Bacterial Infections
- Professor of Medicine
- Duke University Medical Center
- Section Editor
- Stephen B Calderwood, MD
Stephen B Calderwood, MD
- Editor-in-Chief — Infectious Diseases
- Section Editor — Bacterial Infections
- Professor of Medicine (Microbiology and Immunobiology)
- Harvard Medical School
- Deputy Editor
- Anna R Thorner, MD
Anna R Thorner, MD
- Co-Director, Editorial Projects — UpToDate
- Deputy Editor — Infectious Diseases
- Assistant Professor of Medicine, Part-time
- Harvard Medical School
- Translators
- 王翠兰, 主任医师,教授
王翠兰, 主任医师,教授
- 山东大学齐鲁医院神经内科
引言
尽管有效的抗生素疗法可用于治疗细菌性脑膜炎,但该病仍继续导致显著的并发症发病率和死亡率。死亡或发生并发症的风险与以下因素相关:患者的年龄和一般健康状况、致病病原体、就诊时病情的严重程度和持续时间,偶尔也与抗生素治疗延误相关。 (参见“成人细菌性脑膜炎的初始治疗和预后”)
细菌性脑膜炎的并发症可分为全身性和神经系统性。全身性并发症通常是常伴随脑膜炎出现的菌血症的后果,如脓毒性休克、弥散性血管内凝血、急性呼吸窘迫综合征,以及化脓性或反应性关节炎[1]。
细菌性脑膜炎的神经系统并发症包括:
●精神状态受损
●颅内压增高和脑水肿
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