影响儿童眼外肌的肌病
- Authors
- Andrew G Lee, MD
Andrew G Lee, MD
- Professor of Ophthalmology, Neurology, and Neurological Surgery
- Weill Cornell College of Medicine
- Paul W Brazis, MD
Paul W Brazis, MD
- Section Editor — Neuroophthalmology
- Professor of Neurology, Department of Ophthalmology
- Mayo Clinic College of Medicine
- Section Editors
- Evelyn A Paysse, MD
Evelyn A Paysse, MD
- Section Editor — Pediatric Ophthalmology
- Professor of Ophthalmology and Pediatrics
- Baylor College of Medicine
- Marc C Patterson, MD, FRACP
Marc C Patterson, MD, FRACP
- Section Editor — Pediatric Neurology
- Professor of Neurology, Pediatrics, and Medical Genetics
- Chair, Division of Child and Adolescent Neurology
- Mayo Clinic College of Medicine
- Deputy Editor
- Carrie Armsby, MD, MPH
Carrie Armsby, MD, MPH
- Senior Deputy Editor — UpToDate
- Deputy Editor — Pediatrics
- University of Massachusetts School of Medicine
- Translators
- 王军, 副主任医师
王军, 副主任医师
- 广东省人民医院眼科
概述
大多数全身性肌病并不影响眼外肌。然而，也有一些例外值得注意。慢性进行性眼外肌麻痹(chronic progressive external ophthalmoplegia, CPEO)是一个非特异性术语，用来描述一系列累及眼外肌的肌病。这些进行性眼肌麻痹包括：
- 孤立性CPEO
- Kearns-Sayre综合征
- 眼咽型肌营养不良
- 强直性肌营养不良
- 肌管性肌病
进行性眼肌麻痹应与静止性眼肌麻痹区分，后者包括：
- 眼外肌缺如
- 先天性纤维化综合征(参见“儿童垂直斜视的病因”，关于‘先天性眼外肌纤维化’一节)
- 先天性肌病(如，中央核肌病、中央轴空肌病、多轴空肌病)(参见“先天性肌病”)
线粒体肌病经常累及眼外肌，如Kearns-Sayre综合征[1]。线粒体肌病也可表现为面部、延髓和肢体肌病；神经系统表现，如共济失调、痉挛、周围神经病变、耳聋、痴呆；其他眼部表现，如视神经萎缩、视网膜色素变性；心脏传导异常；胃肠运动异常；以及内分泌、皮肤和骨骼异常。 (参见“对代谢性肌病的认识”)
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To continue reading this article, you must log in with your personal, hospital, or group practice subscription. For more information or to purchase a personal subscription, click below on the option that best describes you:Literature review current through: 2017-06 . | This topic last updated: 2017-03-23.The content on the UpToDate website is not intended nor recommended as a substitute for medical advice, diagnosis, or treatment. Always seek the advice of your own physician or other qualified health care professional regarding any medical questions or conditions. The use of this website is governed by the UpToDate Terms of Use ©2017 UpToDate, Inc.References- Carta A, D'Adda T, Carrara F, Zeviani M. Ultrastructural analysis of extraocular muscle in chronic progressive external ophthalmoplegia. Arch Ophthalmol 2000; 118:1441.
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