UpToDate
Official reprint from UpToDate®
www.uptodate.com ©2017 UpToDate®

腹膜透析患者腹腔和胸腔缺陷的诊断方法

Author
Madhukar Misra, MD, FRCP
Section Editor
Steve J Schwab, MD
Deputy Editor
Alice M Sheridan, MD
Translators
毛志国, 副主任医师,副教授

引言

透析液在腹腔内会增加腹内压,并可能导致透析液从腹壁和胸壁的获得性或先天性缺陷处渗漏。这可能表现为胸腔积液、疝或生殖器/腹壁水肿。 (参见“腹膜透析管的非感染性并发症”“持续腹膜透析的非感染性并发症”“持续性腹膜透析中的腹壁疝”)

先前就已有各种诊断方法用于帮助诊断这些缺陷。在20世纪70年代,常使用X线平片、导管对比造影显像和腹膜造影术。然而,由于这些方法稍微不够准确并具有误导性[1],已被放射学方法所替代。这些较新的方法包括使用造影剂/染剂的同位素扫描(腹膜闪烁成像)、计算机断层成像(computed tomography, CT)扫描[CT腹膜造影术(CT peritoneography, CTP)]和磁共振成像(magnetic resonance imaging, MRI)[磁共振腹膜造影术(MR peritoneography, MRP)]。

这篇专题将讨论用于检测腹膜透析(peritoneal dialysis, PD)患者的腹壁和胸壁缺陷的诊断方法。对PD患者的一般问题的综述,包括提示疝、腹膜漏和/或胸膜漏的临床表现,参见其他专题。 (参见“腹膜透析管的非感染性并发症”)

腹膜闪烁成像

腹膜闪烁成像是诊断腹腔漏的一种安全、准确且快速的方法[2-5]。含有3-5毫居里锝-99m的0.5-2L的透析溶液被注入腹腔,然后采用多个投射位(前位,侧位,后位和斜位)以帮助将腹壁漏与其后的腹膜液区分开[6]。

尽管使用了大剂量的同位素,但其并不会被腹膜吸收,且几乎所有的同位素物质在成像检查后都会被排出体外,因此辐射的净剂量仅为滴注入腹膜腔的总剂量的一小部分[7]。

        

Subscribers log in here

To continue reading this article, you must log in with your personal, hospital, or group practice subscription. For more information or to purchase a personal subscription, click below on the option that best describes you:
Literature review current through: 2017-06 . | This topic last updated: 2015-12-07.
The content on the UpToDate website is not intended nor recommended as a substitute for medical advice, diagnosis, or treatment. Always seek the advice of your own physician or other qualified health care professional regarding any medical questions or conditions. The use of this website is governed by the UpToDate Terms of Use ©2017 UpToDate, Inc.
References
Top
  1. Singal K, Segel DP, Bruns FJ, et al. Genital edema in patients on continuous ambulatory peritoneal dialysis. Report of 3 cases and review of the literature. Am J Nephrol 1986; 6:471.
  2. Juergensen PH, Rizvi H, Caride VJ, et al. Value of scintigraphy in chronic peritoneal dialysis patients. Kidney Int 1999; 55:1111.
  3. Walker JV, Fish MB. Scintigraphic detection of abdominal wall and diaphragmatic peritoneal leaks in patients on continuous ambulatory peritoneal dialysis. J Nucl Med 1988; 29:1596.
  4. Goh AS, Lee GS, Kee SG, et al. Radionuclide detection of dialysate leakage in patients on continuous ambulatory peritoneal dialysis. Ann Acad Med Singapore 1994; 23:315.
  5. Johnson J, Baum S, Smink RD Jr. Radionuclide imaging in the diagnosis of hernias related to peritoneal dialysis. Arch Surg 1987; 122:952.
  6. Berman C, Velchik MG, Shusterman N, Alavi A. The clinical utility of the Tc-99m SC intraperitoneal scan in CAPD patients. Clin Nucl Med 1989; 14:405.
  7. Johnson BF, Segasby CA, Holroyd AM, et al. A method for demonstrating subclinical inguinal herniae in patients undergoing peritoneal dialysis: the isotope 'peritoneoscrotogram'. Nephrol Dial Transplant 1987; 2:254.
  8. Leak LV, Rahil K. Permeability of the diaphragmatic mesothelium: the ultrastructural basis for "stomata". Am J Anat 1978; 151:557.
  9. Twardowski ZJ, Tully RJ, Ersoy FF, Dedhia NM. Computerized tomography with and without intraperitoneal contrast for determination of intraabdominal fluid distribution and diagnosis of complications in peritoneal dialysis patients. ASAIO Trans 1990; 36:95.
  10. Sissons GR, Jones SM, Evans C, Richards AR. Scintigraphic detection of abdominal hernias associated with continuous ambulatory peritoneal dialysis. Br J Radiol 1991; 64:1158.
  11. Gudit S, Sudhakar P, Ram R, et al. Peritoneal scintigraphy in the diagnosis of adhesions. Perit Dial Int 2010; 30:112.
  12. Hollett MD, Marn CS, Ellis JH, et al. Complications of continuous ambulatory peritoneal dialysis: evaluation with CT peritoneography. AJR Am J Roentgenol 1992; 159:983.
  13. Lam MF, Lo WK, Chu FS, et al. Retroperitoneal leakage as a cause of ultrafiltration failure. Perit Dial Int 2004; 24:466.
  14. Prokesch RW, Schima W, Schober E, et al. Complications of continuous ambulatory peritoneal dialysis: findings on MR peritoneography. AJR Am J Roentgenol 2000; 174:987.
  15. Arbeiter KM, Aufricht C, Mueller T, et al. MRI in the diagnosis of a peritoneal leak in continuous ambulatory peritoneal dialysis. Pediatr Radiol 2001; 31:745.
  16. Prischl FC, Muhr T, Seiringer EM, et al. Magnetic resonance imaging of the peritoneal cavity among peritoneal dialysis patients, using the dialysate as "contrast medium". J Am Soc Nephrol 2002; 13:197.
  17. Tang S, Chui WH, Tang AW, et al. Video-assisted thoracoscopic talc pleurodesis is effective for maintenance of peritoneal dialysis in acute hydrothorax complicating peritoneal dialysis. Nephrol Dial Transplant 2003; 18:804.
  18. Benz RL, Schleifer CR. Hydrothorax in continuous ambulatory peritoneal dialysis: successful treatment with intrapleural tetracycline and a review of the literature. Am J Kidney Dis 1985; 5:136.
  19. O'Sullivan JC. Letter: Female sterility produced by investigation. Br Med J 1973; 4:490.
  20. Camilleri B, Glancey G, Pledger D, Williams P. The icodextrin black line sign to confirm a pleural leak in a patient on peritoneal dialysis. Perit Dial Int 2004; 24:197.