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儿童腹部钝挫伤中的肝、脾及胰腺损伤

Author
David E Wesson, MD
Section Editor
Susan B Torrey, MD
Deputy Editor
James F Wiley, II, MD, MPH
Translators
洪玉才, 副主任医师

引言

肝脾损伤是儿童钝挫伤中最常见且可能危及生命的腹腔内损伤(intraabdominal injury, IAI)。胰腺损伤并不常见,但如果有大的胰管断裂,则可能导致腹膜炎或假性囊肿。这3种损伤类型的预后都主要取决于是否存在合并伤,尤其是脑和胸部损伤。

本专题将总结儿童腹部钝挫伤中肝、脾及胰腺损伤的诊断和治疗。儿童腹部钝挫伤的一般处理方法,儿童腹部钝挫伤后空腔脏器损伤的诊断和治疗将单独讨论。 (参见“Overview of blunt abdominal trauma in children”“Hollow viscus blunt abdominal trauma in children”)

流行病学

腹部钝挫伤占儿童损伤的10%-15%[1]。实体器官损伤在严重创伤儿童中很常见,其中单纯脾损伤最多见[2]。肝、脾和胰腺损伤有两种典型的形式:直接打击上腹部所致的单纯性损伤,或者由高能机制(如,机动车辆或全地形车碰撞事故、从高处坠落)导致的多系统损伤[1]。这些器官的单纯性损伤更常见,但合并多系统损伤者更可能危及生命,有报道称其死亡率高达12%[3]。

相关解剖

肝、脾及胰腺位于上腹部,部分受肋骨保护。儿童的这种保护作用不如成人,因为他们的肋骨很软,而且肝脾可向下延伸至肋缘下,在婴幼儿中尤其如此。此外,儿童的内脏相对较大、脂肪覆盖较少、且腹部肌肉组织较薄弱。儿童中几乎所有肝、脾及胰腺损伤都由钝性暴力造成。损伤机制可能是直接打击上腹部使腹壁变形、急骤减速所致的供血血管撕裂、肋骨骨折端刺伤或这些脏器被挤压在脊柱上。

由于肝脾血供丰富,这些脏器损伤可导致致命性失血,这些失血要么来自脏器实质,要么来自为其提供血供的动静脉。肝脾都具有重要的生理功能,但如果其他所有方法都无法止血,则可完全切除脾脏。

                     

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Literature review current through: 2017-06 . | This topic last updated: 2016-10-25.
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References
Top
  1. Gaines BA. Intra-abdominal solid organ injury in children: diagnosis and treatment. J Trauma 2009; 67:S135.
  2. Wilson RH, Moorehead RJ. Management of splenic trauma. Injury 1992; 23:5.
  3. Pariset JM, Feldman KW, Paris C. The pace of signs and symptoms of blunt abdominal trauma to children. Clin Pediatr (Phila) 2010; 49:24.
  4. Schafermeyer R. Pediatric trauma. Emerg Med Clin North Am 1993; 11:187.
  5. Oldham KT, Guice KS, Ryckman F, et al. Blunt liver injury in childhood: evolution of therapy and current perspective. Surgery 1986; 100:542.
  6. Rance CH, Singh SJ, Kimble R. Blunt abdominal trauma in children. J Paediatr Child Health 2000; 36:2.
  7. Miller D, Garza J, Tuggle D, et al. Physical examination as a reliable tool to predict intra-abdominal injuries in brain-injured children. Am J Surg 2006; 192:738.
  8. Nance ML, Holmes JH 4th, Wiebe DJ. Timeline to operative intervention for solid organ injuries in children. J Trauma 2006; 61:1389.
  9. Hoffman MA, Spence LJ, Wesson DE, et al. The pediatric passenger: trends in seatbelt use and injury patterns. J Trauma 1987; 27:974.
  10. Young KD, Seidel JS. Delayed diagnosis of splenic injury after falls from less than 10 feet. Pediatr Emerg Care 1998; 14:413.
  11. McIndoe, AH. Delayed heamorrhage following traumatic rupture of the spleen. Br J Surg 1931; 20:249.
  12. Leppäniemi A, Haapiainen R, Standertskjöld-Nordenstam CG, et al. Delayed presentation of blunt splenic injury. Am J Surg 1988; 155:745.
  13. Simpson RA, Ajuwon R. Occult splenic injury: delayed presentation manifesting as jaundice. Emerg Med J 2001; 18:504.
  14. Saladino RA, Lund DP. Abdominal trauma. In: Textbook of Pediatric Emergency Medicine, Fleisher GR, Ludwig S, Henretig FM (Eds), Lippincott Williams & Wilkins, Philadelphia 2006. p.1453.
  15. Capraro AJ, Mooney D, Waltzman ML. The use of routine laboratory studies as screening tools in pediatric abdominal trauma. Pediatr Emerg Care 2006; 22:480.
  16. Valentino M, Serra C, Pavlica P, et al. Blunt abdominal trauma: diagnostic performance of contrast-enhanced US in children--initial experience. Radiology 2008; 246:903.
  17. Wesson DE, Filler RM, Ein SH, et al. Ruptured spleen--when to operate? J Pediatr Surg 1981; 16:324.
  18. Waltzman, ML, Mooney, DP. Major Trauma. In: The Textbook of Pediatric Emergency Medicine, 6th edition, Fleisher, GR, Ludwig, S (Eds), Lippincott, Williams & Wilkins, Philadelphia 2010. p.1244.
  19. Tataria M, Nance ML, Holmes JH 4th, et al. Pediatric blunt abdominal injury: age is irrelevant and delayed operation is not detrimental. J Trauma 2007; 63:608.
  20. Holmes JH 4th, Wiebe DJ, Tataria M, et al. The failure of nonoperative management in pediatric solid organ injury: a multi-institutional experience. J Trauma 2005; 59:1309.
  21. Davies DA, Pearl RH, Ein SH, et al. Management of blunt splenic injury in children: evolution of the nonoperative approach. J Pediatr Surg 2009; 44:1005.
  22. Stylianos S. Evidence-based guidelines for resource utilization in children with isolated spleen or liver injury. The APSA Trauma Committee. J Pediatr Surg 2000; 35:164.
  23. Stylianos S. Outcomes from pediatric solid organ injury: role of standardized care guidelines. Curr Opin Pediatr 2005; 17:402.
  24. Stylianos S. Compliance with evidence-based guidelines in children with isolated spleen or liver injury: a prospective study. J Pediatr Surg 2002; 37:453.
  25. Leinwand MJ, Atkinson CC, Mooney DP. Application of the APSA evidence-based guidelines for isolated liver or spleen injuries: a single institution experience. J Pediatr Surg 2004; 39:487.
  26. Gross JL, Woll NL, Hanson CA, et al. Embolization for pediatric blunt splenic injury is an alternative to splenectomy when observation fails. J Trauma Acute Care Surg 2013; 75:421.
  27. Kiankhooy A, Sartorelli KH, Vane DW, Bhave AD. Angiographic embolization is safe and effective therapy for blunt abdominal solid organ injury in children. J Trauma 2010; 68:526.
  28. Naess PA, Gaarder C, Dormagen JB. Nonoperative management of pediatric splenic injury with angiographic embolization. J Pediatr Surg 2005; 40:e63.
  29. Ohtsuka Y, Iwasaki K, Okazumi S, et al. Management of blunt hepatic injury in children: usefulness of emergency transcatheter arterial embolization. Pediatr Surg Int 2003; 19:29.
  30. Landau A, van As AB, Numanoglu A, et al. Liver injuries in children: the role of selective non-operative management. Injury 2006; 37:66.
  31. David Richardson J, Franklin GA, Lukan JK, et al. Evolution in the management of hepatic trauma: a 25-year perspective. Ann Surg 2000; 232:324.
  32. Stylianos S. Abdominal packing for severe hemorrhage. J Pediatr Surg 1998; 33:339.
  33. Cloutier DR, Baird TB, Gormley P, et al. Pediatric splenic injuries with a contrast blush: successful nonoperative management without angiography and embolization. J Pediatr Surg 2004; 39:969.
  34. Davies DA, Ein SH, Pearl R, et al. What is the significance of contrast "blush" in pediatric blunt splenic trauma? J Pediatr Surg 2010; 45:916.
  35. Lynn KN, Werder GM, Callaghan RM, et al. Pediatric blunt splenic trauma: a comprehensive review. Pediatr Radiol 2009; 39:904.
  36. Davies DA, Fecteau A, Himidan S, et al. What's the incidence of delayed splenic bleeding in children after blunt trauma? An institutional experience and review of the literature. J Trauma 2009; 67:573.
  37. Herman R, Guire KE, Burd RS, et al. Utility of amylase and lipase as predictors of grade of injury or outcomes in pediatric patients with pancreatic trauma. J Pediatr Surg 2011; 46:923.
  38. Hall RI, Lavelle MI, Venables CW. Use of ERCP to identify the site of traumatic injuries of the main pancreatic duct in children. Br J Surg 1986; 73:411.
  39. Canty TG Sr, Weinman D. Treatment of pancreatic duct disruption in children by an endoscopically placed stent. J Pediatr Surg 2001; 36:345.
  40. Houben CH, Ade-Ajayi N, Patel S, et al. Traumatic pancreatic duct injury in children: minimally invasive approach to management. J Pediatr Surg 2007; 42:629.
  41. Wood JH, Partrick DA, Bruny JL, et al. Operative vs nonoperative management of blunt pancreatic trauma in children. J Pediatr Surg 2010; 45:401.
  42. Wales PW, Shuckett B, Kim PC. Long-term outcome after nonoperative management of complete traumatic pancreatic transection in children. J Pediatr Surg 2001; 36:823.
  43. de Blaauw I, Winkelhorst JT, Rieu PN, et al. Pancreatic injury in children: good outcome of nonoperative treatment. J Pediatr Surg 2008; 43:1640.
  44. Burnweit C, Wesson D, Stringer D, Filler R. Percutaneous drainage of traumatic pancreatic pseudocysts in children. J Trauma 1990; 30:1273.
  45. Nellensteijn D, Porte RJ, van Zuuren W, et al. Paediatric blunt liver trauma in a Dutch level 1 trauma center. Eur J Pediatr Surg 2009; 19:358.
  46. Kristoffersen KW, Mooney DP. Long-term outcome of nonoperative pediatric splenic injury management. J Pediatr Surg 2007; 42:1038.
  47. Moore HB, Vane DW. Long-term follow-up of children with nonoperative management of blunt splenic trauma. J Trauma 2010; 68:522.