早产儿的生长管理
- Author
- Ian J Griffin, MB ChB
Ian J Griffin, MB ChB
- Professor, Department of Pediatrics
- UC-Davis, Sacramento, CA
- Section Editors
- Steven A Abrams, MD
Steven A Abrams, MD
- Section Editor — Neonatology
- Professor, Department of Pediatrics
- Dell Medical School at the University of Texas at Austin
- Kathleen J Motil, MD, PhD
Kathleen J Motil, MD, PhD
- Section Editor — Pediatric Nutrition
- Professor of Pediatric Nutrition
- Baylor College of Medicine
- Deputy Editor
- Melanie S Kim, MD
Melanie S Kim, MD
- Senior Deputy Editor — UpToDate
- Deputy Editor — Pediatrics
- Boston University School of Medicine
- Translators
- 王亚娟, 主任医师,副教授
王亚娟, 主任医师,副教授
- 首都医科大学附属北京儿童医院新生儿中心
引言
婴儿早期是细胞大量增生和增大的一个时期,婴儿早期的生长障碍可导致永久性不利影响。该时期内的生长异常可能会持续至成年期,尤其是早产儿。一项有关极低出生体重(very low birth weight, VLBW,<1500g)婴儿的报道对此进行了阐述,这些儿童的身高在20岁时低于第三百分位数的可能性是正常出生体重对照组的2倍(10% vs 5%)[1]。
不论是在新生儿重症监护病房(neonatal intensive care unit, NICU)中还是离开NICU后,早产儿都有生长不佳的风险。必须对他们进行密切监测,还可能需要给予一些干预措施来促进更好生长。
本文将讨论早产儿的生长,包括在NICU中和出院后的生长监测及生长障碍处理。
标准生长数据
目前已有健康足月儿的标准生长数据。然而,早产儿在住院期间及出院后的数据都很有限。 (参见“婴儿和青春期前儿童的正常生长模式”,关于‘生长评价’一节)
足月儿 — 现已有足月儿晚期妊娠时宫内生长和婴儿期生长的标准数据[2,3]。
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To continue reading this article, you must log in with your personal, hospital, or group practice subscription. For more information or to purchase a personal subscription, click below on the option that best describes you:Literature review current through: 2017-06 . | This topic last updated: 2017-06-06.The content on the UpToDate website is not intended nor recommended as a substitute for medical advice, diagnosis, or treatment. Always seek the advice of your own physician or other qualified health care professional regarding any medical questions or conditions. The use of this website is governed by the UpToDate Terms of Use ©2017 UpToDate, Inc.References- Hack M, Flannery DJ, Schluchter M, et al. Outcomes in young adulthood for very-low-birth-weight infants. N Engl J Med 2002; 346:149.
- Costarino AT Jr, Baumgart S. Water as Nutrition. In: Nutritional Needs of the Preterm Infant: Scientific Basis and Practical Guidelines, Tsang RC, et al (Eds), William and Wilkins, Baltimore 1992.
- Babson SG. Growth of low-birth-weight infants. J Pediatr 1970; 77:11.
- Ehrenkranz RA, Younes N, Lemons JA, et al. Longitudinal growth of hospitalized very low birth weight infants. Pediatrics 1999; 104:280.
- Lubchenco LO, Hansman C, Boyd E. Intrauterine growth in length and head circumference as estimated from live births at gestational ages from 26 to 42 weeks. Pediatrics 1966; 37:403.
- Lucas A, Gore SM, Cole TJ, et al. Multicentre trial on feeding low birthweight infants: effects of diet on early growth. Arch Dis Child 1984; 59:722.
- Griffin IJ. Nutritional assessment in preterm infants. Nestle Nutr Workshop Ser Pediatr Program 2007; 59:177.
- Fenton TR, Kim JH. A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants. BMC Pediatr 2013; 13:59.
- Bertino E, Spada E, Occhi L, et al. Neonatal anthropometric charts: the Italian neonatal study compared with other European studies. J Pediatr Gastroenterol Nutr 2010; 51:353.
- Olsen IE, Groveman SA, Lawson ML, et al. New intrauterine growth curves based on United States data. Pediatrics 2010; 125:e214.
- Fenton TR, Nasser R, Eliasziw M, et al. Validating the weight gain of preterm infants between the reference growth curve of the fetus and the term infant. BMC Pediatr 2013; 13:92.
- Cooke RJ, Embleton ND. Feeding issues in preterm infants. Arch Dis Child Fetal Neonatal Ed 2000; 83:F215.
- Embleton NE, Pang N, Cooke RJ. Postnatal malnutrition and growth retardation: an inevitable consequence of current recommendations in preterm infants? Pediatrics 2001; 107:270.
- Guilfoy VM, Wright-Coltart S, Leitch CA, Denne SC. Energy expenditure in extremely low birth weight infants near time of hospital discharge. J Pediatr 2008; 153:612.
- Olsen IE, Lawson ML, Meinzen-Derr J, et al. Use of a body proportionality index for growth assessment of preterm infants. J Pediatr 2009; 154:486.
- Lemons JA, Bauer CR, Oh W, et al. Very low birth weight outcomes of the National Institute of Child health and human development neonatal research network, January 1995 through December 1996. NICHD Neonatal Research Network. Pediatrics 2001; 107:E1.
- Blackwell MT, Eichenwald EC, McAlmon K, et al. Interneonatal intensive care unit variation in growth rates and feeding practices in healthy moderately premature infants. J Perinatol 2005; 25:478.
- Puckett B, Grover VK, Holt T, Sankaran K. Cue-based feeding for preterm infants: a prospective trial. Am J Perinatol 2008; 25:623.
- Newland L, L'huillier MW, Petrey B. Implementation of cue-based feeding in a level III NICU. Neonatal Netw 2013; 32:132.
- Cooke RJ, Griffin IJ, McCormick K, et al. Feeding preterm infants after hospital discharge: effect of dietary manipulation on nutrient intake and growth. Pediatr Res 1998; 43:355.
- Greer FR. Post-discharge nutrition: what does the evidence support? Semin Perinatol 2007; 31:89.
- Fenton TR. A new growth chart for preterm babies: Babson and Benda's chart updated with recent data and a new format. BMC Pediatr 2003; 3:13.
- Fenton TR, Sauve RS. Using the LMS method to calculate z-scores for the Fenton preterm infant growth chart. Eur J Clin Nutr 2007; 61:1380.
- Manser JI. Growth in the high-risk infant. Clin Perinatol 1984; 11:19.
- Hack M, Breslau N, Weissman B, et al. Effect of very low birth weight and subnormal head size on cognitive abilities at school age. N Engl J Med 1991; 325:231.
- Roberts G, Cheong J, Opie G, et al. Growth of extremely preterm survivors from birth to 18 years of age compared with term controls. Pediatrics 2013; 131:e439.
- Horemuzova E, Amark P, Jacobson L, et al. Growth charts and long-term sequelae in extreme preterm infants--from full-term age to 10 years. Acta Paediatr 2014; 103:38.
- Carver JD. Nutrition for preterm infants after hospital discharge. Adv Pediatr 2005; 52:23.
- Griffin IJ, Cooke RJ. Nutrition of preterm infants after hospital discharge. J Pediatr Gastroenterol Nutr 2007; 45 Suppl 3:S195.
- Young L, Morgan J, McCormick FM, McGuire W. Nutrient-enriched formula versus standard term formula for preterm infants following hospital discharge. Cochrane Database Syst Rev 2012; :CD004696.
- ESPGHAN Committee on Nutrition, Aggett PJ, Agostoni C, et al. Feeding preterm infants after hospital discharge: a commentary by the ESPGHAN Committee on Nutrition. J Pediatr Gastroenterol Nutr 2006; 42:596.
- Koo WW, Hockman EM. Posthospital discharge feeding for preterm infants: effects of standard compared with enriched milk formula on growth, bone mass, and body composition. Am J Clin Nutr 2006; 84:1357.
- Picaud JC, Decullier E, Plan O, et al. Growth and bone mineralization in preterm infants fed preterm formula or standard term formula after discharge. J Pediatr 2008; 153:616.
- Griffin IJ. Postdischarge nutrition for high risk neonates. Clin Perinatol 2002; 29:327.
- Abrams SA, Schanler RJ, Garza C. Bone mineralization in former very low birth weight infants fed either human milk or commercial formula. J Pediatr 1988; 112:956.
- Schanler RJ, Burns PA, Abrams SA, Garza C. Bone mineralization outcomes in human milk-fed preterm infants. Pediatr Res 1992; 31:583.
- Young L, Embleton ND, McCormick FM, McGuire W. Multinutrient fortification of human breast milk for preterm infants following hospital discharge. Cochrane Database Syst Rev 2013; :CD004866.
- O'Connor DL, Khan S, Weishuhn K, et al. Growth and nutrient intakes of human milk-fed preterm infants provided with extra energy and nutrients after hospital discharge. Pediatrics 2008; 121:766.
- Gewolb IH, Bosma JF, Taciak VL, Vice FL. Abnormal developmental patterns of suck and swallow rhythms during feeding in preterm infants with bronchopulmonary dysplasia. Dev Med Child Neurol 2001; 43:454.
- Motion S, Northstone K, Emond A, et al. Early feeding problems in children with cerebral palsy: weight and neurodevelopmental outcomes. Dev Med Child Neurol 2002; 44:40.
- Collins CT, Makrides M, McPhee AJ. Early discharge with home support of gavage feeding for stable preterm infants who have not established full oral feeds. Cochrane Database Syst Rev 2003; :CD003743.
- Ortenstrand A, Waldenström U, Winbladh B. Early discharge of preterm infants needing limited special care, followed by domiciliary nursing care. Acta Paediatr 1999; 88:1024.
- Raddish M, Merritt TA. Early discharge of premature infants. A critical analysis. Clin Perinatol 1998; 25:499.
- Belfort MB, Rifas-Shiman SL, Sullivan T, et al. Infant growth before and after term: effects on neurodevelopment in preterm infants. Pediatrics 2011; 128:e899.
- Johnson DB, Cheney C, Monsen ER. Nutrition and feeding in infants with bronchopulmonary dysplasia after initial hospital discharge: risk factors for growth failure. J Am Diet Assoc 1998; 98:649.
- Wilson DC, McClure G. Energy requirements in sick preterm babies. Acta Paediatr Suppl 1994; 405:60.
- Denne SC. Energy expenditure in infants with pulmonary insufficiency: is there evidence for increased energy needs? J Nutr 2001; 131:935S.
- Boehm G, Bierbach U, Moro G, Minoli I. Limited fat digestion in infants with bronchopulmonary dysplasia. J Pediatr Gastroenterol Nutr 1996; 22:161.
- Chye JK, Gray PH. Rehospitalization and growth of infants with bronchopulmonary dysplasia: a matched control study. J Paediatr Child Health 1995; 31:105.
- Mizuno K, Nishida Y, Taki M, et al. Infants with bronchopulmonary dysplasia suckle with weak pressures to maintain breathing during feeding. Pediatrics 2007; 120:e1035.
- Leitch CA, Ahlrichs J, Karn C, Denne SC. Energy expenditure and energy intake during dexamethasone therapy for chronic lung disease. Pediatr Res 1999; 46:109.
- Brunton JA, Saigal S, Atkinson SA. Growth and body composition in infants with bronchopulmonary dysplasia up to 3 months corrected age: a randomized trial of a high-energy nutrient-enriched formula fed after hospital discharge. J Pediatr 1998; 133:340.
- Atkinson SA. Special nutritional needs of infants for prevention of and recovery from bronchopulmonary dysplasia. J Nutr 2001; 131:942S.
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