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Medline ® Abstract for Reference 25

of '恶性胰胆管梗阻的内镜下支架置入术'

25
TI
A prospective randomised multicentre trial comparing 10 Fr Teflon Tannenbaum stents with 10 Fr polyethylene Cotton-Leung stents in patients with malignant common duct strictures.
AU
England RE, Martin DF, Morris J, Sheridan MB, Frost R, Freeman A, Lawrie B, Deakin M, Fraser I, Smith K
SO
Gut. 2000;46(3):395.
 
BACKGROUND: Stent blockage is a multifactorial process in which stent design and materials, bacteria, proteins, and bile viscosity play a role.
AIMS: To compare the patency of the 10 Fr Teflon Tannenbaum (TT) stent to that of the 10 Fr Cotton-Leung (CL) polyethylene stent with sideholes, in patients with malignant obstructive jaundice.
METHODS: Patients were recruited to this prospective multicentre randomised study if they had a newly diagnosed malignant bile duct stricture below the hilum of the liver suitable for stenting with a 10 Fr stent. Data were collected and monitored by a professional monitoring company. Primary patency was the interval between stent placement and first exchange or death without recurrent jaundice.
RESULTS: 134 consecutive patients were recruited between November 1994 and June 1997; 65 were randomised to the TT stent and 69 to the CL stent. Median patency and 95% confidence intervals were 181 (59, 303) days for the TT stent and 133 (92, 174) days for the CL stent, with no significant difference between the two stents (p=0.49). Median survival and 95% confidence intervals were 115 (71, 159) days for the TT stent and 151 (112, 190) days for the CL stent, with no significant difference between the two stents (p=0.765).
CONCLUSION: Neither Teflon as a stent material nor the Tannenbaum design prolong the patency of plastic stents.
AD
Department of Radiology, South Manchester University Hospitals NHS Trust, Withington, Nell Lane, Manchester M20 2LR, UK.
PMID