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复发性多软骨炎的诊断性评估

Author
Clement J Michet, MD
Section Editor
Peter H Schur, MD
Deputy Editor
Paul L Romain, MD
Translators
唐宁, 主治医师

引言

复发性多软骨炎(relapsing polychondritis, RPC)是一种全身炎症性/退化性疾病过程，可能会潜在损害软骨、特殊感觉器官以及心血管、肾脏和神经系统结构和功能完整性(表 1)。 (参见“复发性多软骨炎的临床表现”)

目前关于RPC病因学和发病机制的了解参见其他专题。 (参见“复发性多软骨炎的病因与发病机制”)

诊断

尚无针对RPC的特异性检查方法。RPC诊断的建立需要结合临床表现、支持性实验室数据、影像学检查方法，以及受累软骨部位的活检。

一系列组织学发现可能出现于受累器官中。部分程度上，具体的发现取决于活检的时机。耳软骨炎和主动脉、气管支气管树、滑膜、肾脏及眼部病变的病理学特征参见其他专题。 (参见“复发性多软骨炎的病理学”)

诊断标准 — 已有2套根据经验得出的诊断标准用于定义RPC。原始标准(McAdam标准)需要存在3个或以上的下列临床特征[1]：

                    

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Literature review current through: 2017-06 . | This topic last updated: 2016-10-17.
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