UpToDate
Official reprint from UpToDate®
www.uptodate.com ©2017 UpToDate, Inc. and/or its affiliates. All Rights Reserved.

Medline ® Abstract for Reference 48

of '腹膜后软组织肉瘤的临床特征、评估及治疗'

48
TI
Surgical technique, morbidity, and outcome of primary retroperitoneal sarcoma involving inferior vena cava.
AU
Fiore M, Colombo C, Locati P, Berselli M, Radaelli S, Morosi C, Casali PG, Gronchi A
SO
Ann Surg Oncol. 2012 Feb;19(2):511-8. Epub 2011 Jul 27.
 
BACKGROUND: Retroperitoneal sarcomas (RSTS) involving inferior vena cava (IVC) are rare entities. Vascular resection and reconstruction represent a technical challenge. The aim of the study was to review a monoinstitutional series of IVC resections for RSTS (mainly IVC leiomyosarcoma), focusing on the type of vascular replacement, morbidity, and oncologic outcome.
METHODS: From January 2004 to January 2011, 15 patients (7 male, 8 female) surgically treated for RSTS involving primarily or secondarily IVC were included.
RESULTS: A total of ten patients had IVC replacement and one had partial IVC resection (anterior wall). En bloc organ resection was performed in 14 patients (93%). Major venous reconstructions were performed using PTFE prosthesis (2) or banked venous homografts (8). In four patients IVC reconstruction was not necessary because of the presence of efficient collaterals. Early clinically relevant complications (grade≥3) were detected in one patient (7%) (symptomatic graft thrombosis). No reoperations were needed. No late relevant complications (grade≥3) were observed. Overall graft patency was 60%. At a median follow up of 31.6 months, local recurrence, distant metastases, and survival rate were 20, 26, and 80%, respectively. Complete tumor resection was achieved in all patients.
CONCLUSIONS: IVC resection is safe and well tolerated in RSTS patients. The need for vascular reconstruction has to be assessed according to preoperative imaging, intraoperative findings, and extent of resection. The specific role of banked venous homografts needs to be investigated in larger studies.
AD
Department of Surgery, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy. marco.fiore@istitutotumori.mi.it
PMID