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Medline ® Abstract for Reference 25

of '腹膜后软组织肉瘤的临床特征、评估及治疗'

25
TI
Percutaneous core needle biopsy in retroperitoneal sarcomas does not influence local recurrence or overall survival.
AU
Wilkinson MJ, Martin JL, Khan AA, Hayes AJ, Thomas JM, Strauss DC
SO
Ann Surg Oncol. 2015 Mar;22(3):853-8. Epub 2014 Sep 5.
 
BACKGROUND: Tumours within the retroperitoneum can cause a diagnostic dilemma. A preoperative core needle biopsy often is required to establish a histological diagnosis. Preoperative core needle biopsy for extremity soft-tissue sarcoma is oncologically safe and biopsy site recurrence is extremely rare, attributed to placing the biopsy site within the planned resection field. This study investigates whether preoperative core needle biopsy affects oncological outcomes in retroperitoneal sarcomas.
METHODS: Patients undergoing resection of intermediate- and high-grade primary retroperitoneal sarcoma from 1990 until 2011 were included. Primary endpoints were immediate biopsy-related complications, local recurrence, and overall survival.
RESULTS: A total of 150 patients were included in the analysis. Of these, 90 patients underwent resection after a preoperative biopsy. Median follow-up was 48 months. One patient required hospital admission postbiopsy for an abdominal wall rectus sheath haematoma. No patient developed intra-abdominal complications that required hospitalisation or earlyoperation related to core needle biopsy. No patient developed a biopsy site recurrence. There was no significant increase in either local recurrence (p = 0.101) or overall survival (p = 0.191) after core needle biopsy.
CONCLUSIONS: Preoperative core needle biopsy for retroperitoneal sarcomas is safe and does not affect oncological outcome.
AD
Sarcoma Unit, Department of Surgery, Royal Marsden NHS Foundation Trust, London, UK.
PMID