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Medline ® Abstract for Reference 40

of '肝病患者的化疗肝毒性和剂量调整'

40
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Cyclophosphamide-associated hepatotoxicity.
AU
Goldberg JW, Lidsky MD
SO
South Med J. 1985;78(2):222.
 
Cyclophosphamide, a potent alkylating agent, is effective therapy for some rheumatic diseases. Despite primary hepatic activation of the drug, hepatic toxicity has been reported only in one case. We have reported two episodes of hepatic dysfunction associated with oral cyclophosphamide administration in patients with systemic rheumatic diseases.
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PMID