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Medline ® Abstract for Reference 106

of '肝病患者的化疗肝毒性和剂量调整'

106
TI
Probable azathioprine hepatotoxicity: a case report.
AU
Small P, Lichter M
SO
Ann Allergy. 1989;62(6):518.
 
A patient with polymyositis was treated initially with corticosteroids. Subsequently, azathioprine was added but was associated with transient hepatotoxicity on two separate occasions, 6 months apart. Both episodes occurred 3 weeks after starting the latter drug. This is the first case of azathioprine toxicity documented by both histopathology and drug challenge.
AD
Division of Allergy and Clinical Immunology, SMBD-Jewish General Hospital, Montreal, Quebec, Canada.
PMID