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睡眠时异常动作和行为的概述

Author
Bradley V Vaughn, MD
Section Editor
Alon Y Avidan, MD, MPH
Deputy Editor
April F Eichler, MD, MPH
Translators
陈兴泳, 副主任医师

引言

睡眠时异常动作和行为是一大群夜间事件的组成部分,可能发生在睡眠、觉醒,或睡眠与觉醒互相转换时期。这些事件最常见于生命早期,约15%-20%的儿童和4%的成年人受累[1-4]。

夜间事件通常分为简单行为(如,单一的动作、重复或周期性动作、节律性动作)和复杂行为(如,梦呓、睡行症、夜惊、梦境表演)(表 1)。大多数简单动作发生在觉醒-睡眠或睡眠-觉醒转换期间,或发生在浅睡非快动眼睡眠相(non-rapid eye movement, NREM)期间(图 1)。复杂行为可源于觉醒、NREM和快速眼睡眠相(rapid eye movement, REM)3个正常状态的控制机制被破坏。

偶尔,睡眠时简单或复杂的运动模式是癫痫发作、精神分裂事件,甚至诸如低血糖等生理状态的表现。因此,临床医生应意识到夜间事件可能是特定神经疾病、内科疾病、精神病、或睡眠障碍的一种表现。另一方面,儿童时期的一些夜间行为可能是正常的,特别是觉醒障碍和噩梦。

详细的病史是确定基础病因线索的基础,病史包括患者及他人的详细描述(最好是床伴或见证的家人).临床医生面临的挑战是需识别出某些夜间事件何时标志着某种可治疗的基础疾病,何时表示一种新出现的神经系统异常,以及何时是一种年龄相符的良性发作。

本专题介绍一种评估和诊断睡眠期间异常动作和行为的方法。其他关于发生于儿童和成人的特异性异态睡眠和睡眠相关运动障碍的诊断和治疗参见其他专题。 (参见“儿童睡行症及其他深眠状态”“成人非快动眼睡眠觉醒障碍”“快动眼睡眠相睡眠行为障碍”“不安腿综合征”“儿童不安腿综合征/Willis-Ekbom病和周期性肢体运动障碍”)

                   

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Literature review current through: 2017-07 . | This topic last updated: 2015-10-06.
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References
Top
  1. International Classification of Sleep Disorders, 3rd ed, American Academy of Sleep Medicine, Darien, IL 2014.
  2. Ohayon MM, Mahowald MW, Dauvilliers Y, et al. Prevalence and comorbidity of nocturnal wandering in the U.S. adult general population. Neurology 2012; 78:1583.
  3. Ohayon MM, Guilleminault C, Priest RG. Night terrors, sleepwalking, and confusional arousals in the general population: their frequency and relationship to other sleep and mental disorders. J Clin Psychiatry 1999; 60:268.
  4. Kales A, Soldatos CR, Bixler EO, et al. Hereditary factors in sleepwalking and night terrors. Br J Psychiatry 1980; 137:111.
  5. Sharpless BA. Exploding head syndrome. Sleep Med Rev 2014; 18:489.
  6. Ohayon MM. Prevalence of hallucinations and their pathological associations in the general population. Psychiatry Res 2000; 97:153.
  7. Silber MH, Hansen MR, Girish M. Complex nocturnal visual hallucinations. Sleep Med 2005; 6:363.
  8. Wichniak A, Tracik F, Geisler P, et al. Rhythmic feet movements while falling asleep. Mov Disord 2001; 16:1164.
  9. Bassetti C, Vella S, Donati F, et al. SPECT during sleepwalking. Lancet 2000; 356:484.
  10. Oliviero A, Della Marca G, Tonali PA, et al. Functional involvement of cerebral cortex in adult sleepwalking. J Neurol 2007; 254:1066.
  11. Sharpless BA, McCarthy KS, Chambless DL, et al. Isolated sleep paralysis and fearful isolated sleep paralysis in outpatients with panic attacks. J Clin Psychol 2010; 66:1292.
  12. Germain A, Nielsen TA. Sleep pathophysiology in posttraumatic stress disorder and idiopathic nightmare sufferers. Biol Psychiatry 2003; 54:1092.
  13. Hobson JA. REM sleep and dreaming: towards a theory of protoconsciousness. Nat Rev Neurosci 2009; 10:803.
  14. Schenck CH, Milner DM, Hurwitz TD, et al. A polysomnographic and clinical report on sleep-related injury in 100 adult patients. Am J Psychiatry 1989; 146:1166.
  15. Schenck CH, Mahowald MW. REM sleep behavior disorder: clinical, developmental, and neuroscience perspectives 16 years after its formal identification in SLEEP. Sleep 2002; 25:120.
  16. Vaughn BV, Ali I. Sleep and epilepsy: opportunities for diagnosis and treatment. Neurol Clin 2012; 30:1249.
  17. D'Cruz OF, Vaughn BV. Nocturnal seizures mimic REM behavior disorder. Am J Electroneurodiagnostic Technol 1997; 37:258.
  18. Brassington GS, King AC, Bliwise DL. Sleep problems as a risk factor for falls in a sample of community-dwelling adults aged 64-99 years. J Am Geriatr Soc 2000; 48:1234.
  19. Papadimitriou GN, Linkowski P. Sleep disturbance in anxiety disorders. Int Rev Psychiatry 2005; 17:229.
  20. Levin R, Nielsen TA. Disturbed dreaming, posttraumatic stress disorder, and affect distress: a review and neurocognitive model. Psychol Bull 2007; 133:482.
  21. Rice E, Fisher C. Fugue states in sleep and wakefulness: a psychophysiological study. J Nerv Ment Dis 1976; 163:79.
  22. Merckelbach H, Dekkers T, Wessel I, Roefs A. Amnesia, flashbacks, nightmares, and dissociation in aging concentration camp survivors. Behav Res Ther 2003; 41:351.
  23. Boeve BF, Molano JR, Ferman TJ, et al. Validation of the Mayo Sleep Questionnaire to screen for REM sleep behavior disorder in a community-based sample. J Clin Sleep Med 2013; 9:475.
  24. Manni R, Terzaghi M, Repetto A. The FLEP scale in diagnosing nocturnal frontal lobe epilepsy, NREM and REM parasomnias: data from a tertiary sleep and epilepsy unit. Epilepsia 2008; 49:1581.
  25. Chen LF, Lin CE, Chou YC, et al. A comparison of complex sleep behaviors with two short-acting Z-hypnosedative drugs in nonpsychotic patients. Neuropsychiatr Dis Treat 2013; 9:1159.
  26. Pressman MR, Mahowald MW, Schenck CH, Bornemann MC. Alcohol-induced sleepwalking or confusional arousal as a defense to criminal behavior: a review of scientific evidence, methods and forensic considerations. J Sleep Res 2007; 16:198.
  27. Dyken ME, Afifi AK, Lin-Dyken DC. Sleep-related problems in neurologic diseases. Chest 2012; 141:528.
  28. Prashad PS, Marcus CL, Brown LW, et al. Brain tumor presenting as somnambulism in an adolescent. Pediatr Neurol 2013; 49:209.
  29. Bell DS. Nocturnal hypoglycaemia presenting as somnambulism. Diabetologia 2010; 53:2066.
  30. Foldvary-Schaefer N, Alsheikhtaha Z. Complex nocturnal behaviors: nocturnal seizures and parasomnias. Continuum (Minneap Minn) 2013; 19:104.
  31. Postuma RB, Aarsland D, Barone P, et al. Identifying prodromal Parkinson's disease: pre-motor disorders in Parkinson's disease. Mov Disord 2012; 27:617.
  32. Kushida CA, Littner MR, Morgenthaler T, et al. Practice parameters for the indications for polysomnography and related procedures: an update for 2005. Sleep 2005; 28:499.
  33. Pilon M, Montplaisir J, Zadra A. Precipitating factors of somnambulism: impact of sleep deprivation and forced arousals. Neurology 2008; 70:2284.
  34. Pilon M, Zadra A, Joncas S, Montplaisir J. Hypersynchronous delta waves and somnambulism: brain topography and effect of sleep deprivation. Sleep 2006; 29:77.