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Medline ® Abstract for Reference 48

of 'Vitamin D deficiency in adults: Definition, clinical manifestations, and treatment'

48
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ACOG Committee Opinion No. 495: Vitamin D: Screening and supplementation during pregnancy.
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ACOG Committee on Obstetric Practice
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Obstet Gynecol. 2011;118(1):197.
 
During pregnancy, severe maternal vitamin D deficiency has been associated with biochemical evidence of disordered skeletal homeostasis, congenital rickets, and fractures in the newborn. At this time, there is insufficient evidence to support a recommendation for screening all pregnant women for vitamin D deficiency. For pregnant women thought to be at increased risk of vitamin D deficiency, maternal serum 25-hydroxyvitamin D levels can be considered and should be interpreted in the context of the individual clinical circumstance. When vitamin D deficiency is identified during pregnancy, most experts agree that 1,000–2,000 international units per day of vitamin D is safe. Higher dose regimens used for treatment of vitamin D deficiency have not been studied during pregnancy. Recommendations concerning routine vitamin D supplementation during pregnancy beyond that contained in a prenatal vitamin should await the completion of ongoing randomized clinical trials.
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PMID