Vitamin D deficiency in residents of academic long-term care facilities despite having been prescribed vitamin D

J Am Med Dir Assoc. 2007 Feb;8(2):71-5. doi: 10.1016/j.jamda.2006.07.005. Epub 2006 Oct 27.

Abstract

Objectives: Vitamin D is vitally important in maintaining skeletal health. A low plasma vitamin D concentration is associated with increased parathyroid hormone secretion, increased bone turnover, osteomalacia, and osteoporosis. As a result, vitamin D deficiency is associated with a higher incidence of hip and other fractures. Although Vitamin D deficiency has been reported in long-term care facilities, optimal methods of replenishment have not been defined. The objective of the present study was to identify the pattern of calcium and vitamin D supplementation in nursing home residents and to identify vitamin D deficiency in residents already on supplement therapy.

Design: Retrospective chart review.

Setting: Five academic nursing homes staffed by faculty from the University of Arkansas for Medical Sciences.

Participants: Elderly residents aged 65 and older receiving calcium and vitamin D supplements.

Measurements: Data on dose, frequency, and levels of calcium and vitamin D were collected. The medication list and creatinine levels were also recorded.

Results: Forty-four (40%) residents were receiving 1000 mg, 48 (44%) were receiving 1200 mg, and 9 (8.2%) were receiving 1500 mg of calcium carbonate. Similarly, 79 (72%) residents were on 400 IU, 13 (12%) were on 600 IU, and only 8 (7%) were on 800 IU of vitamin D3 (cholecalciferol). Low levels of Vitamin D 25 (OH) D (values <30 ng/mL) were identified in 49.4% of residents; 16% were found to have deficiency (<20 ng/mL).

Conclusion: Despite clear benefit, nursing home residents were not supplemented adequately with calcium and vitamin D.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Arkansas / epidemiology
  • Bone Density Conservation Agents / therapeutic use*
  • Calcifediol / blood
  • Calcifediol / deficiency
  • Calcium Carbonate / therapeutic use
  • Cross-Sectional Studies
  • Drug Monitoring
  • Drug Utilization Review
  • Faculty, Medical
  • Female
  • Fractures, Bone / etiology
  • Geriatrics / statistics & numerical data
  • Humans
  • Male
  • Medical Audit
  • Nursing Homes / statistics & numerical data*
  • Practice Patterns, Physicians' / statistics & numerical data*
  • Retrospective Studies
  • Risk Factors
  • Treatment Outcome
  • Vitamin D / physiology
  • Vitamin D / therapeutic use*
  • Vitamin D Deficiency / diagnosis
  • Vitamin D Deficiency / epidemiology*
  • Vitamin D Deficiency / prevention & control*

Substances

  • Bone Density Conservation Agents
  • Vitamin D
  • Calcium Carbonate
  • Calcifediol