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Medline ® Abstract for Reference 22

of 'Vestibular neuritis and labyrinthitis'

Vestibular neuritis: vertigo and the high-acceleration vestibulo-ocular reflex.
Palla A, Straumann D, Bronstein AM
J Neurol. 2008;255(10):1479. Epub 2008 Jul 11.
Patients after vestibular neuritis (VN) often report persistent dizziness and disequilibrium. We correlated persistent symptoms with sustained impairment of the high-acceleration horizontal vestibulo-ocular reflex as determined by quantitative searchcoil head-impulse testing (qHIT). In 47 patients, qHIT was recorded 0-60 months and symptoms assessed with the Yardley Vertigo Symptom Scale short form>or = 18 months after VN onset. No correlation between the magnitude of high-acceleration vestibular impairment and the severity of vertigo symptoms was observed. The lack of a symptom-qHIT correlation suggests that defective compensation at a more rostral level in the central nervous system may be responsible for protracted symptoms in VN patients.
Neurology Department, Zurich University Hospital, Frauenklinikstrasse 26, 8091 Zurich, Switzerland.