Medline ® Abstract for Reference 99
of 'Vagus nerve stimulation therapy for the treatment of epilepsy'
99
TI
Vagus nerve stimulation for epilepsy: randomized comparison of three stimulation paradigms.
AU
DeGiorgio C, Heck C, Bunch S, Britton J, Green P, Lancman M, Murphy J, Olejniczak P, Shih J, Arrambide S, Soss J
SO
Neurology. 2005;65(2):317.
Vagus nerve stimulation (VNS) is an effective adjunctive treatment for intractable epilepsy. However, the optimal range of device duty-cycles [on/(on + off times)]is poorly understood. The authors performed a multicenter, randomized trial of three unique modes of VNS, which varied primarily by duty-cycle. The results indicate that the three duty-cycles were equally effective. The data support the use of standard duty-cycles as initial therapy.
AD
UCLA-Geffen School of Medicine, Los Angeles, CA, USA. cmd@mednet.ucla.edu
PMID