Medline ® Abstract for Reference 52
of 'Vagus nerve stimulation therapy for the treatment of epilepsy'
52
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Effectiveness of vagus nerve stimulation in epilepsy patients: a 12-year observation.
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Uthman BM, Reichl AM, Dean JC, Eisenschenk S, Gilmore R, Reid S, Roper SN, Wilder BJ
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Neurology. 2004;63(6):1124.
A retrospective review of the safety, tolerability, and efficacy of vagus nerve stimulation (VNS) in 48 patients with intractable partial epilepsy was performed. Side effects were few and mild to moderate. Mean seizure frequency decreased by 26% after 1 year, 30% after 5 years, and 52% after 12 years with VNS treatment.
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Neurology Service, Malcom Randall Department of Veterans Affairs Medical Center, University of Florida College of Medicine and McKnight Brain Institute, Gainesville 32608, USA. basim.uthman@med.va.gov
PMID