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Unipolar depression in adults: Clinical features

Jeffrey M Lyness, MD
Section Editor
Peter P Roy-Byrne, MD
Deputy Editor
David Solomon, MD


Depression occurs along a continuum of severity, and depressive syndromes such as unipolar major depression are heterogeneous [1]. The multiple presentations of major depression stem in part from the several subtypes that have been identified and the many comorbid disorders that frequently occur.

This topic reviews the clinical features of depression in adults. The assessment, diagnosis, epidemiology, neurobiology, treatment, and prognosis of depression in adults are discussed separately, as are the clinical features and diagnosis of depression in pediatric and older adult patients:

(See "Unipolar depression in adults: Assessment and diagnosis".)

(See "Unipolar depression in adults: Epidemiology, pathogenesis, and neurobiology".)

(See "Unipolar major depression in adults: Choosing initial treatment".)


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Literature review current through: Dec 2016. | This topic last updated: Sat Jan 14 00:00:00 GMT+00:00 2017.
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