Medline ® Abstract for Reference 38
of 'Tricyclic antidepressant poisoning'
Asystole complicating physostigmine treatment of tricyclic antidepressant overdose.
Pentel P, Peterson CD
Ann Emerg Med. 1980;9(11):588.
Physostigmine is a commonly used therapy for the anticholinergic manifestations of tricyclic antidepressant (TCA) overdose. We describe two patients with TCA toxicity who developed asystole following the administration of physostigmine to treat seizures.