Treatment, prognosis, and prevention of Listeria monocytogenes infection
- Michael S Gelfand, MD
Michael S Gelfand, MD
- Professor of Medicine
- University of Tennessee College of Medicine
- Section Editors
- Daniel J Sexton, MD
Daniel J Sexton, MD
- Editor-in-Chief — Infectious Diseases
- Section Editor — Bacterial Infections
- Professor of Medicine
- Duke University Medical Center
- Morven S Edwards, MD
Morven S Edwards, MD
- Section Editor — Pediatric Infectious Diseases
- Professor of Pediatrics
- Baylor College of Medicine
Listeria monocytogenes is an important bacterial pathogen in neonates, immunosuppressed patients, older adults, pregnant women, and, occasionally, previously healthy individuals. The importance of underlying diseases was illustrated in a series of 165 adults with culture-proven Listeria infection: 69 percent of cases in nonpregnant adults occurred in patients with cancer, AIDS, organ transplant recipients, or corticosteroid therapy .
The treatment and prognosis of listerial infection will be reviewed here. The epidemiology, pathogenesis, clinical manifestations, and diagnosis of listerial infection are discussed separately. (See "Epidemiology and pathogenesis of Listeria monocytogenes infection" and "Clinical manifestations and diagnosis of Listeria monocytogenes infection".)
Treatment varies with the different clinical syndromes of listerial infection:
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- CLINICAL SYNDROMES
- Antibiotic regimens
- - First-line regimens
- - Alternative drugs
- - High-risk patients
- - Febrile gastroenteritis
- - Pregnancy
- Mild symptoms
- Fever with or without other findings
- - Focal infection
- Duration of therapy
- Monitoring during therapy
- PREVENTION OF FOODBORNE INFECTION
- SOCIETY GUIDELINE LINKS
- INFORMATION FOR PATIENTS
- SUMMARY AND RECOMMENDATIONS
- - Type of infection
- - Duration
- - Monitoring